What is the real-world effectiveness of etrasimod in adult patients ages ≥18 years and <65 years with moderately to severely active UC?

The Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) is doing this study because they want to learn more about eosinophilic gastrointestinal disorders (EGIDs).

The study intends to assess the effectiveness of a board exam curricula for a group of gastroenterology fellows. The study aims to assess how prepared this curricula makes the gastroenterology fellows feel, as well as objective impact on in-training exam scores.

The primary objective for this registry is to prospectively study the natural history of IBD, the prevalence and incidence of comorbidities, and targeted adverse events, as well as the utilization patterns and the comparative effectiveness and comparative safety of approved IBD treatments.

The purpose of this research study is to learn more about Barrett's Esophagus and esophageal cancer by collecting data and samples (blood and tissue) for a biorepository. A biorepository is a large bank of specimens and data that are stored indefinitely and may be shared with other researchers.

The purpose of the study is validate the first measure of disease-specific quality of life in patients diagnosed with eosinophilic gastritis (EG) or eosinophilic gastroenteritis (EGE).

This is a 5-year, longitudinal, observational study of adult and pediatric patients (age 2 and above) undergoing IBD therapy designed to specifically address important clinical questions that remain incompletely answered from registration trials. In addition to the study database, a biospecimen repository will also be included so that translational studies of viral resistance, genomics, and biomarkers of response may be performed. Also, the right to collect retrospective data on these IBD patients will be reserved.

The study is designed to look at Crohn's disease over a period time, from before a surgery to 12 months after the surgery has taken place. The role bacteria in the gut plays in Crohn's disease (CD) is not well understood. Which particular microbes contribute to disease remain unknown. In CD, ~70% of patients will end up requiring surgery due to chronic unrelenting complications, and ~50% require additional surgery. We hope to identify key microbes at the time of surgery in stool and tissue and correlate it over time with data collected at timepoints after surgery. We will use this data with clinical information to determine if specific microbes are associated with disease recurrence.

This project will define findings of patients referred for colonoscopy following a positive Cologuard® test using retrospective analysis of one community Gastroenterology practice.

To assess hepatitis C virus treatment and hepatocellular carcinoma surveillance within practices and gauge the feasibility of a program to implement point-of-care risk stratification tools and screening referral systems.