To assess the effects of intervention on histologic disease activity following 12 weeks of treatment

We are studying how to make medical test results easier for patients to understand. Pathology reports, which explain what doctors find in tissue samples, are often written for medical professionals and can be hard for patients to read. In this study, we are testing whether artificial intelligence (AI) can help explain these reports in plain language. Patients having a routine screening procedure will read a sample report with or without an AI-generated explanation. Then they will answer questions about how well they understood the report and how they felt about it. We want to learn if using AI helps people better understand their health information and feel more confident making decisions. This will help improve the way test results are shared in the future.

The purpose of this project is to advance understanding of the relationship of food and eating characteristics with gastrointestinal symptoms on a population level, by examining the frequency, associated factors, and quality of life and emotional effects of eating-associated gastrointestinal symptoms.

The primary objective of this study is to assess the efficacy of different doses of SAR442970 compared with placebo in participants with moderate to severe Ulcerative Colitis.

The Consortium of Eosinophilic Gastrointestinal Disease Researchers (CEGIR) is doing this study because they want to learn more about eosinophilic gastrointestinal disorders (EGIDs).

To understand the relationship between biomarkers (found in the blood) and health outcomes among adults diagnosed with hepatocellular carcinoma who are receiving a liver transplant.

To learn if one kind of treatment approach, either (1) endoscopic surveillance or (2) endoscopic eradication therapy, is better, the same, or worse for treating patients with Barrett's esophagus and low-grade dysplasia.

The purpose of this research study is to learn more about Barrett's Esophagus and esophageal cancer by collecting data and samples (blood and tissue) for a biorepository. A biorepository is a large bank of specimens and data that are stored indefinitely and may be shared with other researchers.

The study is designed to look at Crohn's disease over a period time, from before a surgery to 12 months after the surgery has taken place. The role bacteria in the gut plays in Crohn's disease (CD) is not well understood. Which particular microbes contribute to disease remain unknown. In CD, ~70% of patients will end up requiring surgery due to chronic unrelenting complications, and ~50% require additional surgery. We hope to identify key microbes at the time of surgery in stool and tissue and correlate it over time with data collected at timepoints after surgery. We will use this data with clinical information to determine if specific microbes are associated with disease recurrence.

To assess hepatitis C virus treatment and hepatocellular carcinoma surveillance within practices and gauge the feasibility of a program to implement point-of-care risk stratification tools and screening referral systems.