Have you been infected with COVID-19? Are you a solid organ transplant recipient? Have you or your child received a COVID-19 vaccine or are planning to receive one? If so, you may be eligible to participate in a research study that will assess your immune response to COVID-19 infection or vaccination over a 5 year period. We are looking for children and adults aged 7-95 years, and plan to collect blood every 2-6 months over the study period. (Compensation provided for the first year).

In this study, we want to learn more about a program (STOMP) designed to improve chronic pain in people living with HIV.

The purpose of this study is to conduct interviews to hear people's thoughts and feedback on various aspects of conducting syphilis vaccine research at UNC-Chapel Hill and to ask them to complete a brief online survey after their interviews. The information that participants provide will help the clinical trial researchers to better understand what concerns people might have about syphilis vaccine research and to design clinical trials that are acceptable to potential vaccine research participants.

To comprehensively characterize the clinical, laboratory, and histopathologic features of breast cancer patients receiving care according to local standards in Malawi.

The purpose of this expanded access IND (compassionate use) program is to provide tecovirimat for treatment or prevention of non-variola orthopoxvirus infections (e.g., vaccinia, monkeypox, cowpox or other human virus infection identified as an orthopoxvirus) and secondary treatment of complications from replication-competent vaccinia vaccine in adults and children.

The purpose of this study is to estimate the number of Lyme and other tick-borne disease cases occurring in Biltmore Forest.

To see if hormone therapy (HT) helps reduce hot flashes and night sweats, also known as vasomotor symptoms (VMS), in women living with HIV in the late menopausal transition (similar to what is known as perimenopause) or early post-menopause (the time after the final menstrual period or after removal of both ovaries).

This is a Phase 2 Crossover Study of On Demand PrEP Formulations Comparing Rectal and Oral TFV-Based PrEP

The goal of the ABACUS-HIV Study is to learn about things that make it easier or more difficult for people with HIV to take their cholesterol medication consistently. WHAT WILL YOU BE ASKED TO DO? Be interviewed for 60-75 minutes in clinic or by phone; All your responses will be confidential; Participants will be compensated $50. WHO CAN JOIN? People living with HIV; At least 18 years old; Prescribed a cholesterol medication called a statin; Can speak English; Have agreed to be in the HIV clinic database at UNC. Patients interested in participating should contact the study team at (919) 843-2532.

To find out if certain study treatments (study interventions) can help treat exercise intolerance and post-exertional malaise that started or got worse after a COVID-19 infection and have lasted for at least 3 months