The purpose of this research study is to learn about HIV transmission and strategies for prevention. We are looking for people living with or at risk for HIV in the Raleigh area and learning more about the people they know in the community.

Have you been infected with COVID-19? Are you a solid organ transplant recipient? Have you or your child received a COVID-19 vaccine or are planning to receive one? If so, you may be eligible to participate in a research study that will assess your immune response to COVID-19 infection or vaccination over a 5 year period. We are looking for children and adults aged 7-95 years, and plan to collect blood every 2-6 months over the study period. (Compensation provided for the first year).

This project seeks to adapt and test the existing Tough Talks app to address COVID vaccine hesitancy among African American young adults (AA-YA) aged 18-29.

In this study, we want to learn more about a program (STOMP) designed to improve chronic pain in people living with HIV.

The purpose of this study is to conduct interviews to hear people's thoughts and feedback on various aspects of conducting syphilis vaccine research at UNC-Chapel Hill and to ask them to complete a brief online survey after their interviews. The information that participants provide will help the clinical trial researchers to better understand what concerns people might have about syphilis vaccine research and to design clinical trials that are acceptable to potential vaccine research participants.

The purpose of this research study is to learn from YMSM about their perceptions of two phone apps designed to increase HIV testing, PrEP uptake, and other prevention strategies. We also want to learn about whether the apps encourage behavior change, as they are designed to do.

Aim 1: Among key stakeholders in NC impacted by HIV molecular surveillance (HMS) activities, we aim to assess the ethical concerns surrounding the implementation of HMS and related pubic health services and research by: 1a) Characterizing stakeholders' awareness, experiences with, and sources of information AND 1b) Examining perceptions, including perceived risks and benefits and other ethical considerations, and the opportunities for enhancement of community engagement practices Aim 2: To develop a community-engaged partnership framework to promote effective communication and community participation regarding HMS, and related health services and research.

This is a research study to find out if antiviral or other drugs can help people who have COVID symptoms that have lasted more than 3 months after a COVID infection. This condition is known as Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), including Long COVID.

The purpose of this expanded access IND (compassionate use) program is to provide tecovirimat for treatment or prevention of non-variola orthopoxvirus infections (e.g., vaccinia, monkeypox, cowpox or other human virus infection identified as an orthopoxvirus) and secondary treatment of complications from replication-competent vaccinia vaccine in adults and children.

To better understand whether people in jail have ever received COVID-19 testing and vaccination and whether they would be will to receive these services in jail and after their release.