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Research Studies

UNC-Chapel Hill Division of Infectious Diseases

45 studies match your search
By physician referral or invitation only

Placebo-Controlled Trial of Conserved-Mosaic T-cell Vaccine in a Regimen with Vesatolimod and Broadly Neutralizing Antibodies in Adults Initiated on Suppressive Antiretroviral Therapy during Acute HIV-1

To evaluate safety and efficacy of therapeutic vaccination with chimpanzee adenovirus (ChAdV)- and poxvirus modified vaccinia Ankara (MVA)-vectored vaccines in a sequential regimen with the Toll-like Receptor 7 (TLR7) agonist vesatolimod (VES) and two broadly neutralizing antibodies (bNAbs) in individuals with HIV-1 who started suppressive antiretroviral therapy (ART) during acute HIV-1.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • HIV/AIDS
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

RECOVER-VITAL: A Platform Protocol for Evaluation of Interventions for Viral Persistence, Viral Reactivation, and Immune Dysregulation in Post-Acute Sequelae of SARS-CoV-2 Infection (PASC)

This is a research study to find out if antiviral or other drugs can help people who have COVID symptoms that have lasted more than 3 months after a COVID infection. This condition is known as Post-Acute Sequelae of SARS-CoV-2 Infection (PASC), including Long COVID.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • COVID-19
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

COVID-19 services in jail

To better understand whether people in jail have ever received COVID-19 testing and vaccination and whether they would be will to receive these services in jail and after their release.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • COVID-19
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Pay-it-forward gonorrhea and chlamydia testing among MSM in China: PIONEER RCT

To test the pay-it-forward strategy as a means of increasing rates of testing for gonorrhea

Age & Gender
  • 18 years ~ 99 years
  • Male
Study Interest
  • Behavior
  • Sexual and/or Reproductive Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Does it move the needle? Characterizing long-acting injectable antiretroviral therapy eligibility, uptake, and integration at UNC

To study the use of long-acting injectable antiretroviral therapy (LAI) among a racially, economically, and geographically diverse group of persons with HIV

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • HIV/AIDS
  • Opinions and Perceptions
  • UNC or UNC Health employees
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Mixed methods formative research and pilot testing of a task-shifted adaptation of the WHO-PEN intervention to address cardio-metabolic complications in people living with HIV in Zambia

To learn about more effective ways the health care system in Zambia can care for people with non-communicable diseases (NCDs) who are also living with HIV.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Pressure
  • Diabetes
  • HIV/AIDS
  • Wellness and Lifestyle
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Point of Care Ultrasound Use Among Physician Residents in Lima, Peru

The purpose of this study is to assess ultrasound experience, current use of ultrasound and desire for further training of emergency medicine residents in Lima, Peru. This study also has the purpose of determining perceived barriers to expanding the use of ultrasound

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Behavior
  • Opinions and Perceptions
  • Social or Workplace Dynamics
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Shared Decisions when Choosing between Long-Acting Injecting or Oral Therapy

The SELIGO study assesses perceptions of HIV treatment - including long acting injectable antiretroviral therapy (LAI ART) - among people living with HIV infection (PLWH) and HIV healthcare providers (HCPs) to develop strategies and tools to facilitate shared decision-making by patients and provider considering HIV therapy options.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • HIV/AIDS
  • Immune System/Infections
  • Opinions and Perceptions
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Biobank for COVID-19 Convalescent Samples

The purpose of this research study is to understand if convalescent plasma is a potential therapy and to understand the immune response to COVID-19 infection. Understanding the immune system's response after infection will help to inform vaccine design and the potential role of antibodies as therapeutics in the setting of COVID-19 infection and disease.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Immune System/Infections
  • COVID-19
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

PROMPT HIV Bioethics Supplement Project

Aim 1: Among key stakeholders in NC impacted by HIV molecular surveillance (HMS) activities, we aim to assess the ethical concerns surrounding the implementation of HMS and related pubic health services and research by: 1a) Characterizing stakeholders' awareness, experiences with, and sources of information AND 1b) Examining perceptions, including perceived risks and benefits and other ethical considerations, and the opportunities for enhancement of community engagement practices Aim 2: To develop a community-engaged partnership framework to promote effective communication and community participation regarding HMS, and related health services and research.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Behavior
  • HIV/AIDS
  • Opinions and Perceptions
  • and 3 more
Visit Location
100% Remote (online, phone, text)
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