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Research Studies

UNC-Chapel Hill Division of Infectious Diseases

42 studies match your search
By physician referral or invitation only

Accessible metrics of access: Novel tools to measure immunization coverage

To assess three different metrics of healthcare access as surrogate measures of immunization coverage.

Age & Gender
  • 0 years ~ 99 years
  • Male, Female
Study Interest
  • Child and Teen Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Adapting Community-based Task-shifting for the COVID-19 response among Underserved Populations in NC

This study is partnering with communities to identify the best ways to provide COVID-19 testing and vaccines to people who have been disproportionately affected by COVID-19. This includes communities of color, essential workers, immigrants and migrants, people in rural areas, and people with chronic diseases like diabetes and high blood pressure. We want to train community outreach workers and peer recruiters from community and faith-based organizations to help reach these underserved populations with COVID-19 testing and COVID-19 vaccines - a strategy known as "community-based task shifting." Thus, we will be conducting focus groups and theater testing sessions and questionnaires with patients who have received COVID-19 health services and focus groups and interviews with key stakeholders and theater testing sessions and questionnaires with individuals who work in community outreach or peer health education organizations for COVID-19 health services.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Opinions and Perceptions
  • COVID-19
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Adapting Community-based Task-shifting for the COVID-19 response among Underserved Populations in Piedmont, NC: An Evaluation Protocol

This implementation science study will use mixed methods and an interrupted time series design to evaluate an implementation strategy intended to expand the reach and effectiveness of COVID-19 testing and vaccination services in underserved populations in the Piedmont region of NC. The primary service outcomes (i.e., reach and effectiveness) will be evaluated using review of existing routinely collected data. The primary implementation outcomes will be assessed through mixed methods research with patients who received, and providers who delivered, COVID-19 testing or prevention services, such as vaccination, at a Consortium-supported site such as a Federally Qualified Health Center administered by Piedmont Health. A standardized script will be used to inform potential participants about the study, their research options, and to screen to see if they are preliminarily eligible to take part in the study.

Age & Gender
  • 0 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Opinions and Perceptions
  • COVID-19
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Infection Prevention and Control in Western Uganda

The primary objective of the proposed project is to demonstrate the effects of limited physical facility infrastructure, diminished supplies, and gaps in Infection Prevention and Control (IPC) knowledge among Healthcare Personnel on IPC practice implementation at the health facility level to inform efficient and effective future improvement efforts.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Drug Use-Associated Infective Endocarditis: Patient Perspectives and Treatment Preferences

The purpose of this research study is to learn more about patient preferences for care when undergoing treatment for drug use-associated endocarditis (DUA-IE), specifically treatment for addiction and antibiotic treatment.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Immune System/Infections
  • Substance Use (tobacco, alcohol, opioids, etc)
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

N-803 With and Without Combination bNAbs

The purpose of this study is to investigate if N-803, a new experimental drug that stimulates the immune system, is safe and tolerable when given alone and in combination with two new experimental drugs that are antibodies (natural proteins that the body makes in response to an infection) to HIV (the virus that causes AIDS), VRC07-523LS and 10-1074. This study will also look at how well HIV is controlled after stopping anti-HIV medications (also known as "ART") in persons who received N-803 alone or N-803 with VRC07-523LS and 10-1074.

Age & Gender
  • 18 years ~ 70 years
  • Male, Female, Gender Inclusive
Study Interest
  • HIV/AIDS
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Lassa Study

To provide a much-needed characterization of Lassa fever epidemiology and pathogenesis, and to determine the duration and infectivity of genital fluids from survivors that will provide a wellspring of data to inform public policy and individual care.

Age & Gender
  • 5 years ~ 99 years
  • Male, Female
Study Interest
  • Immune System/Infections
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Pay-it-forward gonorrhea and chlamydia testing among MSM in China: PIONEER RCT

To test the pay-it-forward strategy as a means of increasing rates of testing for gonorrhea

Age & Gender
  • 18 years ~ 99 years
  • Male
Study Interest
  • Behavior
  • Sexual and/or Reproductive Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Does it move the needle? Characterizing long-acting injectable antiretroviral therapy eligibility, uptake, and integration at UNC

To study the use of long-acting injectable antiretroviral therapy (LAI) among a racially, economically, and geographically diverse group of persons with HIV

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • HIV/AIDS
  • Opinions and Perceptions
  • UNC or UNC Health employees
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Assessing access to care following prison release - Provider Perspectives

The purpose of this project is to understand, from the perspective of medical providers and community health workers (CHWs), the barriers and facilitators that people released from prison experience in establishing and engaging with health care, and how those barriers and facilitators may be impacted by participation in the FIT and FIT Connect transitional health care programs.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Opinions and Perceptions
Visit Location
100% Remote (online, phone, text)
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