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UNC-Chapel Hill Department of Neurology

41 studies match your search
Not currently enrolling

BOOST-3

The study is being done to compare two ways of treating patients with a brain injury. At this time medical providers do not know if one way is better than the other. Both ways of treating patients are used in standard of care. None of the treatments in this study are investigational.

Age & Gender
  • 14 years ~ 99 years
  • Male, Female
Study Interest
  • Brain, Head, Nervous System
Open

DLB Consortium

Do you have probable Dementia with Lewy Bodies (DLB), Mild Cognitive Impairment with "high likelihood" DLB, or Parkinson's Disease Dementia (PDD)? You may be able to participate in an observational study to track your disease progression and promote future research.

Age & Gender
  • 40 years ~ 90 years
  • Male, Female
Study Interest
  • Brain, Head, Nervous System
  • Mental and Emotional Health
By physician referral or invitation only

Open Lable Extension of TSC Study

Assess the treatment of Ganaxolone.

Age & Gender
  • 1 years ~ 65 years
  • Male, Female
Study Interest
  • Developmental
  • Rare Diseases
Visit Location
100% Remote (online, phone, text)
Not currently enrolling

Safety and Efficacy of ALXN1720 in Adults with Generalized Myasthenia Gravis

The purpose of this study is to evaluate the safety and efficacy of ALXN1720 for the treatment of generalized MG (gMG) in adults with autoantibodies against AChR (AChR+).

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

A study to investigate the efficacy and safety of efgartigimod PH20 SC in adult participants with active idiopathic inflammatory myopathy

The purpose of this study is to investigate the efficacy and safety of efgartigimod PH20 SC in adults with active idiopathic inflammatory myopathy.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

New Subarachnoid Hemorrhage Drug Study

This study is comparing a drug that treats bleeding in the brain related to a ruptured aneurysm as it is delivered via intravenous (IV) versus via a pill.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

A Brain Anatomy Visual Tool in the Education of Patients with Cognitive Disorders

To determine the helpfulness of using images of brain anatomy to educate patients about their cognitive disorders.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Brain, Head, Nervous System
  • Mental and Emotional Health
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

antiseizure medication and seizure networks in Severe acute brain injury

We want to assess If the abnormal network patterns seen in seizure networks of epilepsy have similar implications when observed in patients with severe acute brain injury and therefore are modulated by antiseizure medication (ASM). If those networks respond to the ASM, then they may have a relationship with epileptogenic brain activity in this clinical context too and therefore could benefit from ASM even though they do not present ictal activity on their EEG.

Age & Gender
  • 6 years ~ 65 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Injury/Injury Prevention
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

HEALEY ALS Platform Trial

The purpose of the HEALEY ALS Platform Trial is to develop and administer various clinical trials under different regimens with ALS to provide multiple treatment options for patients with ALS.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Chronic Conditions
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Non-Invasive Brain Activity Recording and Behavior Research Study

The purpose of this research study is to learn if and how non-invasive brain stimulation influences motivation problems in Parkinson's disease. Men and women aged 55-80 years with Parkinson's disease for at least 5 years can join the study. There are three study visits. Participation will involve answering questions, doing exercises where you squeeze a joystick to earn "rewards", recording of your brain activity, and receiving transcranial magnetic stimulation (TMS).

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Brain, Head, Nervous System
  • Healthy Volunteer or General Population
Visit Location
100% Remote (online, phone, text)
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