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UNC-Chapel Hill Department of Neurology

44 studies match your search
Open

Validation of the Unified Tremor Rating Scale (UTRS)

There is a great need to create a meaningful, tremor assessment tool for clinicians that correlates with patient-related concerns and outcomes. The Unified Tremor Rating Scale has been developed in collaboration with the Movement Disorders Society and needs to be validated with the help of centers around the globe. UNC Chapel Hill has been asked to join this effort and is looking for participants who have Parkinson disease tremor or Essential Tremor who are willing to undergo a series of questionnaires and unique physical examination maneuvers

Age & Gender
  • 18 years ~ 89 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Movement
Open

Regulating Together in TSC

We are looking for kids, ages 8-18 and their caregivers to join us for a research study to learn new techniques to deal with emotional dysregulation and behavior intervention. This study will includes one in person visit, and all other remaining visits and groups to occur within the comfort of your own home!

Age & Gender
  • 8 years ~ 18 years
  • Male, Female
Study Interest
  • Behavior
  • Genetics and Genetic Disorders
Open

A randomized open label trial examining the effectiveness of Ofatumumab versus current therapy on relapsing multiple sclerosis.

Are you between 18 and 45 years of age and diagnosed with multiple sclerosis, without MS relapses within the past year? Are you currently prescribed with MS medication? If so, you may be able to participate in a research study examining whether a switch to a high-efficacy medication- Ofatumumab, would work better for you than your current treatment.

Age & Gender
  • 18 years ~ 45 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Immune System/Infections
Open

IMVT Batoclimab Efficacy and Safety

The purpose of the current Phase 3 study is to confirm the effectiveness and safety of batoclimab in participants with generalized Myasthenia Gravis in 2 different doses of batoclimab compared to placebo.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Not currently enrolling

Circadian rhythm in rock climbing performance

Circadian rhythm is well known to affect various aspects of sports performance; however, the sport specific effects in rock climbing are not well studied. We aim to evaluate diurnal changes in maximum finger strength, finger endurance, and power in rock climbers.

Age & Gender
  • 18 years ~ 65 years
  • Male, Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
Open

Parkinson's Disease Genetic Registry

Have you or a family member been diagnosed with Parkinson's Disease? Would you be interested in helping researchers learn more about Parkinson's by giving a blood or saliva sample? If so, you may be eligible to participate in a research study that will utilize genetic testing to provide you more information about the possible roles of your genes in your diagnosis.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Genetics and Genetic Disorders
  • Movement
Open

Phase 2 Study of ALXN2050 in Generalized Myasthenia Gravis

Study is being conducted to ubderstand the effectiveness of ALXN2050 compared with placebo in the treatment of generalized MG (gMG) based on improvement in the Myasthenia Gravis Activities of Daily Living (MG-ADL) total score

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Not currently enrolling

Zynerba 033

This is a randomized, double-blind, placebo-controlled, multiple-center study, to assess the efficacy and safety of CBD administered as ZYN002, a transdermal gel, for the treatment of children and adolescent patients with FXS.

Age & Gender
  • 3 years ~ 18 years
  • Male, Female, Gender Inclusive
Study Interest
  • Child and Teen Health
  • Developmental
  • Parents of Children
Open

Non-invasive brain stimulation for Parkinson's non-motor symptoms

Are you interested in advancing treatments in Parkinson's disease? Did you know that the non-motor symptoms of Parkinson's disease are often very disabling and can lead to poor outcomes with the disease? If you have Parkinson's disease, you may be eligible to take part in a research study to learn if we can use non-invasive brain stimulation to treat these symptoms in Parkinson's disease

Age & Gender
  • 50 years ~ 90 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Brain, Head, Nervous System
  • Mental and Emotional Health
  • and 4 more
Open

Cartesian_CD08_MG-001

Autoimmune MG is a antibody-mediated disease with 85% of patients have disease mediated by AChR or anti-MUSK antibodies. Study aims to use T-cells engineered CAR T cells that will kill targeted cells directly.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Bones, Joints, Muscles
  • Brain, Head, Nervous System
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