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UNC-Chapel Hill Department of Neurology

37 studies match your search
Open

Circadian rhythm in rock climbing performance

Are you a rock climber serious about climbing harder? You may be able to participate in research that will guide training and maximum performance.

Age & Gender
  • 18 years ~ 65 years
  • Male, Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
Open

Phase 2 Study of ALXN2050 in Generalized Myasthenia Gravis

Study is being conducted to ubderstand the effectiveness of ALXN2050 compared with placebo in the treatment of generalized MG (gMG) based on improvement in the Myasthenia Gravis Activities of Daily Living (MG-ADL) total score

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Open

Biogen Intuition

Biogen Intuition is a virtual research study for people between the ages of 50 and 86 with mild cognitive impairment made by a health care provider within the last two years. You can help researchers learn how Apple Watch and iPhone can be used to learn more about brain health!

Age & Gender
  • 50 years ~ 86 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
Visit Location
100% Remote (online, phone, text)
Not currently enrolling

Zynerba 033

This is a randomized, double-blind, placebo-controlled, multiple-center study, to assess the efficacy and safety of CBD administered as ZYN002, a transdermal gel, for the treatment of children and adolescent patients with FXS.

Age & Gender
  • 3 years ~ 18 years
  • Male, Female, Gender Inclusive
Study Interest
  • Child and Teen Health
  • Developmental
  • Parents of Children
Open

Non-invasive brain stimulation for Parkinson's non-motor symptoms

Are you interested in advancing treatments in Parkinson's disease? Did you know that the non-motor symptoms of Parkinson's disease are often very disabling and can lead to poor outcomes with the disease? If you have Parkinson's disease, you may be eligible to take part in a research study to learn if we can use non-invasive brain stimulation to treat these symptoms in Parkinson's disease

Age & Gender
  • 50 years ~ 90 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Brain, Head, Nervous System
  • Mental and Emotional Health
  • and 4 more
Open

Pharnext CLN-PXT3003-06 PREMIER study

There is currently no approved drug for the treatment of CMT1A, nor medical guidelines for the management of the disease. Supportive therapies mainly address aspects of neuropathic pain and limb deformities. The most useful supportive treatments include treatment of pain (anti-inflammatory/analgesics, anti-depressants, or anti-convulsive drugs for neuropathic pain), physiotherapy (muscle strength training), occupational therapy, orthopedic devices (including braces and high top shoes) as well as orthopedic surgery. However, these treatments are not sufficient to limit progressive impairment of motor function and worsening of disability. Considering the debilitating nature of the disease and the absence of a specific therapy, there remains a pressing unmet medical need for an efficacious and safe treatment for CMT1A

Age & Gender
  • 16 years ~ 65 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Open

Cartesian_CD08_MG-001

Autoimmune MG is a antibody-mediated disease with 85% of patients have disease mediated by AChR or anti-MUSK antibodies. Study aims to use T-cells engineered CAR T cells that will kill targeted cells directly.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Bones, Joints, Muscles
  • Brain, Head, Nervous System
Open

Genetic Determinants of Neurological and Developmental Disorders

Do or your family have any neurological or developmental disorders that are genetically unexplained? Would you be interested in helping researchers learn more about these disorders by providing a blood sample?

Age & Gender
  • 0 days ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Developmental
  • Genetics and Genetic Disorders
  • Rare Diseases
Not currently enrolling

Lorcaserin for Dravet Syndrome

The purpose of this study is to assess the safety (symptoms and medical problems your child may experience -known as side effects) and efficacy (how well and for how long the study works) of the study drug on subjects who have Dravet syndrome.

Age & Gender
  • 2 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Genetics and Genetic Disorders
  • Rare Diseases
Open

Long-erm extension study for ARGX-113-1802- safety and tolerability of efgartigimod in patients with CIDP

An unmet medical need exists for an efficacious treatment of CIDP with a favorable safety and tolerability profile and more convenient administration than that provided by current treatments. A weekly subcutaneous (SC) treatment option consisting of efgartigimod PH20 SC administered within a few minutes could offer clinically significant benefits to CIDP patients.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Immune System/Infections
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