This study compares two dose strengths of a new epilepsy medicine to placebo for treatment of refractory focal onset epilepsy as measured by the change in 28-day average seizure frequency.

This clinical trial aims to understand how well ALXN-C5IT works over a long time. We want to see if it can prevent relapses and help with disability, walking, and vision. We also want to know how patients feel about their health while using ALXN-C5IT.

TO EVALUATE THE SAFE AND EFFECTIVE USE OF A ZILUCOPLAN AUTO-INJECTOR COMBINATION PRODUCT FOR SUBCUTANEOUS SELF-ADMINISTRATION BY STUDY PARTICIPANTS

This is a study being conducted at many sites across the US to evaluate patients who are older than 50 years old, who have sudden bleeding in the brain (intracerebral hemorrhage) while taking a statin medication. It is unclear if continuing to take a statin medication after this type of injury can increase the risk of another hemorrhage, stroke or cardiac event. This study will assign patients to 1 of 2 groups. One group will continue the statin medication they were taking previously. The other group will discontinue the statin medication. Both groups will be followed for 2 years to see if they have any additional medical events.

The purpose of this study is to create a biorepository of blood samples form patients with myasthenia gravis that may be used with collaborators in the development of new therapeutics for myasthenia gravis (MG).