Ever wonder how the way you walk may affect your knees? Have you ever had an ACL reconstruction? You may be able to take part in a study to learn more about how different types of force applied to your legs can affect your knee while walking on a treadmill.

Have you recently had an anterior cruciate ligament injury and will be undergoing anterior cruciate ligament reconstruction surgery? If so, you may be able to participate in a study comparing the effects on pain relief and arthritis prevention of metformin or placebo. Compensation provided.

We are conducting a research study to use graded exposure and mobile mindfulness meditation to address clinical outcomes in individuals 6-months to 10-years post-ACLR. This will help develop effective treatments to improve outcomes after ACLR. This study will last 5 weeks. Compensation provided.

Do you have a history of ACL reconstruction? You may be eligible to participate in a study using virtual reality and mindfulness meditation! We aim to explore psychological factors that may impact return to play outcomes after ACL reconstruction.

The purpose of this project is to quantitatively and qualitatively examine the adherence and acceptability of the Oura Ring, and to examine the accuracy of the Oura Ring to measure physical activity. *This study is a collaboration with the UNC Sports Medicine Institute*

Interested in participating in future research studies? Whether you have had a previous ACL injury or not, you may be able to take part in several research study opportunities. This registry simply collects your contact information and then we will reach out if any study opportunities are available.

The purpose of the study is to understand gait patterns of healthy, uninjured individuals. *This study is a collaboration with the UNC Sports Medicine Institute*

Have you had ACL reconstruction? You may be able to participate in a research study examining how brain function might change after surgery. Compensation provided.

The Lower Extremity Assessment Protocol (LEAP) is a program to prevent reinjury and promote long-term health by characterizing muscle function, evaluating movement performance, and monitoring patient-reported outcomes (e.g., pain). The purpose of this study is to learn more about the outcomes following orthopaedic surgery after a lower limb injury. *This study is a collaboration with the UNC Sports Medicine Institute*

Many young athletes who tear their ACL have trouble getting back to sport or suffer a second ACL injury once they do. We aim to improve athletes' ability to get back to sport safely. We want to make the activities athletes perform in rehabilitation more closely match the demands of what they do once they return to their sport. We also aim to develop low-cost ways to measure how the knee is moving during those activities. *This study is a collaboration with the UNC Sports Medicine Institute*