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Research Studies

UNC-Chapel Hill Lineberger Comprehensive Cancer Center

241 studies match your search
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An Acute Leukemia Study

Do you have Acute Myeloid Leukemia, Myelodysplastic Syndrome, or Chronic Myelomonocytic Leukemia? Are you looking for other treatment options? We are doing a study to find out whether treatment with the study drug (Bexmarilimab) along with standard treatment can help your cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Leukemia)

Characterization of Circulating Tumor DNA Kinetics During Radiation Therapy, Treatment Monitoring, and Surveillance: A Pilot Study in Hematologic and Pediatric Malignancies

This is a prospective study that will look for the kinetics of circulating tumor DNA (ctDNA) in patients with hematologic and pediatric cancer before and after undergoing standard of care treatment regimens where radiation therapy is a treatment.

Age & Gender
  • 2 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Pediatric Cancers, Lymphoma)
Open

Mirvetuximab Soravtansine With Bevacizumab Versus Bevacizumab as Maintenance in Platinum-sensitive Ovarian, Fallopian Tube, or Peritoneal Cancer

Do you have ovarian cancer that has come back after your first round of treatment? if so you may be able to participate in a research study to test if MIRV in combination with bevacizumab as maintenance therapy, can help to prevent your cancer from returning or delaying your cancer's return.

Age & Gender
  • 18 years ~ 99 years
  • Female
Study Interest
  • Cancer (Other Cancers, Ovarian)
Open

Study of ISB 2001 in Relapsed/Refractory Multiple Myeloma

Have you been diagnosed with relapsed or refractory multiple myeloma? If so, you may be able to take part in a research study looking at the safety of giving a new drug to patients with multiple myeloma.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Multiple Myeloma)

Ruxolitinib in Patients with High Risk and Premalignant Breast Conditions

To determine the difference in change in apoptosis between diagnosis and surgery as a function of ruxolitinib treatment versus placebo, among participants with high-risk or premalignant breast conditions.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Breast)
Open

Study of sacituzumab govitecan with or without pembrolizumab in Metastatic TNBC

Have you been diagnosed with triple negative breast cancer? If so, you may be able to take part in a research study looking at the safety of giving a new drug called Sacituzumab Govitecan with or without a drug called Pembrolizumab to patients with PDL-1-negative metastatic triple negative breast cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Breast)
Open

SAMURAI Study- Stereotactic radiation therapy with immune therapy for patients with Renal Cell Cancer

Do you have renal cell cancer that has spread beyond your kidney and surgery is not recommended? You may be able to take part in a research study to help us learn if adding radiation therapy to your usual cancer treatment may help your cancer shrink.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Kidney)
Open

LCCC 1855/MASCOT: Manufacturing and Analysis of Stem Cells from Skin Cells for Ovarian Cancer Treatment

Are you suspected of having or have been diagnosed with ovarian cancer? if so, you may be able to participate in a research study looking at creating personalized stem cells from the skin of ovarian cancer patients to see if these stem cells can attack cancer cells. This work may be able to help us find more treatment options for ovarian cancer patients in the future.

Age & Gender
  • 18 years ~ 99 years
  • Female
Study Interest
  • Cancer (Ovarian)
Open

Radiation, PARP inhibition, and immunotherapy for breast cancer brain metastasis

Have you been diagnosed with breast cancer with brain metastases? If so, you may be able to take part in a research study looking at the safety of giving a new drug called olaparib concurrently (at the same time) with stereotactic radiosurgery, followed by immunotherapy and chemotherapy, to patients with breast cancer with brain metastases.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Cancer (Brain and Other Nervous System, Breast)
Open

Study for Blood Cancer

Have you been diagnosed with Leukemia? You may be able to take part in a research study to find out if a new study drug can help put your blood cancer into remission.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Leukemia)
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