The purpose of this trial is to allow patients who are currently on the PROSERA trial to receive medication until the study drug is commercially available.

This study aims to understand how people think about issues and benefits associated with AI, and how they communicate with other about this topic.

This study seeks to determine the best practices for boosting the Mobile Crisis Workforce in Illinois. Right now, there is a massive shortage of people to help during mental health crises, and it is very important that we figure out how to fix this issue.

This study explores the response of the adjacent gum tissue to a type of dental filling material.

We are looking for links between cystic fibrosis outcomes and a history of intimate partner violence.

To explore community pharmacist perspectives on the feasibility of and interest in pharmacy-centered methadone access at rural community pharmacies. The model for which we will elicit pharmacists' perspectives parallels several similar successful programs that exist outside of the US and several successful small-scale pilots that have been conducted in urban areas of the US, including NC.

To explore people with lived and living experience (PWLLE) of opioid use and/or taking methadone on the feasibility of and interest in pharmacy-centered methadone access at rural community pharmacies. The model for which we will elicit PWLLE perspectives parallels several similar successful programs that exist outside of the US and several successful small-scale pilots that have been conducted in urban areas of the US, including NC.

Hunter Syndrome or Mucopolysaccharidosis II (MPS II) is a rare genetic disorder caused by decreased levels of a specific enzyme, iduronate-2-sulfatase. Lack of this enzyme causes buildup of large sugar molecules called glycosaminoglycans (GAGs). The build up of GAGs causes significant damage to the body and brain. This extension study is evaluating the long-term safety and efficacy of JR-141, an enzyme replacement therapy, to provide the missing enzyme to the body. This allows for break down of the stored GAGs. JR-141 uses specific technology to cross the blood brain barrier so that the enzyme can get into the brain. JR-141 is expected to help both the cognitive (brain) and body effects of MPS II.

This study aims to understand how Exercise and Sport Science (EXSS) students use generative AI (GenAI) for everyday and coursework purposes, and the barriers and facilitators to its use in these settings. GenAI is growing in use among college students and it is important to understand how students apply this technology into their college education.

We are performing a clinical study to determine the optimal frequency for medications for infected pleural fluid, referred to as intrapleural enzyme therapy (IET). Participants will either receive once daily IET or twice daily IET. We hypothesize that once daily IET will be non-inferior to twice daily IET.