We are aiming to create and test a questionnaire that measures symptoms related to a condition called eosinophilic esophagitis

This study aims to design and improve tools that can be used to select strategies for improving colorectal cancer screening in different settings and populations. Interviews, surveys, and focus groups will be conducted with individuals who make decisions related to colorectal cancer screening interventions about their understanding, preferences, and suggestions related to these tools and intervention strategies.

About two in five people who are undergoing a kidney biopsy have diabetes. Diabetes is a common finding in people with kidney disease, but little is known about the specific ways in which diabetes affects kidney function. The purpose of this study is to gather two groups of patients with diabetes who undergo a kidney biopsy in order to create a source of information with genetic, blood, and urine samples available, by which researchers can study how diabetes affects kidney function.

To evaluate the impact on learning patient-centered care in the context of trauma assessments using a virtual reality educational compared to a traditional powerpoint tool.

We propose to develop and test health messages about e-cigarettes and study their impact. Findings will inform e-cigarette warning policies and communication campaigns.

This phase II trial studies the effect of nivolumab in combination with blinatumomab compared to blinatumomab alone in treating patients with B-cell acute lymphoblastic leukemia (B-ALL) that has come back (relapsed). Down syndrome patients with relapsed B-ALL are included in this study. Blinatumomab is an antibody, which is a protein that identifies and targets specific molecules in the body. Blinatumomab searches for and attaches itself to the cancer cell. Once attached, an immune response occurs which may kill the cancer cell. Nivolumab is a medicine that may boost a patient's immune system. Giving nivolumab in combination with blinatumomab may cause the cancer to stop growing for a period of time, and for some patients, it may lessen the symptoms, such as pain, that are caused by the cancer.

The purpose of this research study is to evaluate the effects of Sickle Cell Disease on the state of coagulation and effects on generation of certain coagulation proteins. People with sickle cell disease tend to have a higher rate of thrombosis which is not fully understood. Through this study, we hope to gain a better understanding of the effects of sickle cell disease on turning on coagulation that ultimately leads to a thrombotic event.

We will collect stem cells from individuals with autism to investigate brain development in sibling pairs who do not share a diagnosis of ASD, as well as examine associations between brain growth and variation in ASD-related behaviors.

This research uses the Attitudes Related to Trauma-Informed Care (ARTIC) Scale to gauge the readiness of school mental health practitioners (i.e., school psychologists, social workers, and counselors) to shift toward trauma-sensitive systems. Despite the reliance on school mental health practitioners in this movement, little research exists on their preparedness for and training in trauma-informed approaches. In hope of better situating schools to act as buffers against the adverse effects of childhood trauma, this research seeks to inform graduate and professional-level training on disciplinary practice, causes of student behavior, and the protective nature of secure adult relationships.

TCN PATHS is a Justice Community Opioid Innovations Network (JCOIN) study in collaboration with UNC-CH, Yale, The University of Puerto Rico, The Hennepin Research Institute, University of Rochester, University of Connecticut, Albert Einstein College of Medicine, and the University of Miami, aims to improve health outcomes for justice involved persons with Opioid Use Disorder (OUD). Opioid overdose is the leading cause of death, and a common cause of morbidity, after release from jail. Recently, because medications for OUD effectively reduced relapse, recidivism and overdose, several jails have started to treat OUD with medications. However, OUD treatment discontinuation upon release is a persistent problem. The long-term goal of the study is to reduce morbidity and mortality from OUD among justice-involved individuals. The overall objective is to assess whether the Transitions Clinic Network (TCN), which provides enhanced primary care for people released from incarceration in 30 community health centers in the United States,