Have you been diagnosed with high-risk early triple-negative breast cancer (TNBC) without mutations in the BRCA1 or BRCA2 gene? If you still have evidence of TNBC in your breast or lymph node tissue after receiving treatment and surgery, you may qualify for this clinical research study. This study will test an experimental drug combination to find out which treatment is better at delaying the return of cancer.

Have you been diagnosed with cancer and either your cancer did not respond to treatment or your cancer progressed? If so, you may be able to take part in a research study evaluating the safety of an investigational treatment called LOXO-435 in cancer patients.

Do you have endometrial cancer? ]. If so, you may be able to take part in a research study looking at the safety of giving a combination treatment of the drugs ONC201 plus Atezolizumab to patients with endometrial cancer.

Have you been diagnosed with colon cancer? If so, you may be able to take part in a research study looking to find out what kind of chemotherapy to recommend to patients based on the presence or absence of circulating tumor DNA (ctDNA) after surgery for colon cancer and if this approach is better or worse than the usual approach for your colon cancer.

This is a study for people diagnosed with Acute Myeloid Leukemia and Myelodysplastic Syndromes who are receiving treatment with hypomethylating agents and Venetoclax. Specifically, we want to learn more about nutrition, eating, and mealtimes for older adults (age 60+) with these conditions and their care partners. Care partners can be a spouse, family member, or friend helping a patient with AML/MDS. We want to understand nutrition, eating, and mealtimes over time throughout the first two cycles of treatment. We also want to learn more about the quality of life for patients and care partners.

The purpose of this study is to learn more about how an investigational drug (tarlatamab) works in people with extensive-stage small cell lung cancer. In this study, we want to learn more about its safety and tolerability (effects good or bad) when used in combination with one of two other drugs (atezolizumab or durvalumab). We also want to learn more about the combination of the study drug with either atezolizumab or durvalumab and carboplatin and etopopside.

Have you been diagnosed with HER2 positive (HER2+) breast cancer and have recently or plan to undergo surgery? If so, you may be able to take part in a research study looking at the safety of giving two drugs trastuzumab and pertuzumab in combination with hormonal therapy after surgery for your breast cancer.

Are you an elderly patient with locally advanced Head and Neck squamous cell carcinoma who is ineligible for standard treatment involving platinum based therapy (e.g. Carboplatin or Cisplatin)? If so, you may be eligible to participate in a clinical research study involving an investigational drug, called NBTXR3.

In this study, we want to learn more about the experiences and activities of high school-aged youth after a neurological event. This study will also help us to understand the perspectives of youth and a parent/caregiver through photos and stories.

Do you have a solid tumor? Would you like to have screening done to see if you are eligible for a treatment study? If so, you may be able to take part in a study that will look at your tumor sample to see if you are eligible for another investigational treatment study.