The purpose of this research study is to develop a new tool to detect early signs of pain in newborns by using advanced computer technology, or artificial intelligence. The information we learn by doing this study may improve our ability to recognize and assess pain the newborns.

The purpose of this study is to develop a useful computer model that can be used by doctors to diagnose and determine the best medical treatment plan for children diagnosed or suspected to have subglottic stenosis (SGS). SGS can be either congenital (present at birth) or acquired (the result of trauma or infection). Premature infants who require long-term breathing support are at increased risk of developing SGS.

We are exploring what primary care physicians feel is important for them to know about nutrition given their clinical experience, how they would have liked to learn nutrition during their medical training, and desired ways to support them in providing nutrition care in their current practice. We are also evaluating a tool that may make nutrition counseling easier and more efficient for providers. The results of the study can potentially lead to improvements in nutrition training in medicine and quality of nutrition care.

The purpose of this expanded access IND (compassionate use) program is to provide tecovirimat for treatment or prevention of non-variola orthopoxvirus infections (e.g., vaccinia, monkeypox, cowpox or other human virus infection identified as an orthopoxvirus) and secondary treatment of complications from replication-competent vaccinia vaccine in adults and children.

Hypothesis: The development of patient-focused tools and care processes will enable a transition from predominantly office-based CF care to a more convenient, co-produced model. The increased utilization of remote care will be associated with improved adherence to disease monitoring and complication screening guidelines and will increase patient satisfaction. Specific Aims: 1. Customize a patient-facing smartphone application (Nudge) designed to "coach" each patient toward a co-produced goal of convenient and effective health monitoring within the context of enhanced remote care. 2. Develop care processes that facilitate monitoring of respiratory status at home, using home spirometry and remote sputum collection, that include education, electronic reminders, and specimen collection/shipping supplies 3. Implement care processes that allow convenient access to necessary screening procedures, using the Nudge application to provide well-timed electronic reminders and track performance of screening tests.

This study aims to study best practices for future and current educators to use 360° images and videos for teaching and learning. The researchers will survey pre-service and in-service teachers along teacher educators to gain their insights and understandings. The participants will then use a website to build learning experiences that utilize 360° images and videos and ask them about their new understanding and if they have a deeper understanding of using 360° for teaching and learning. This study's benefits will be to gain a better understanding of this topic and develop best practices for supporting educators in using 360° images and videos in the classroom.

The purpose of the study is to understand why it is the case that authors do not submit reproducible research compendia even when a policy requires it (and policy guidance explains how). To do so, the study looks toward the specific mechanisms that inhibit and/or facilitate execution of data management tasks that support reproducibility. Identifying these mechanisms can inform the design of interventions that better equip researchers to produce and share high-quality research compendia. Such interventions may reduce the amount of time and labor currently required for current data verification workflows, which in turn may make journal-based data policies more feasible for a greater number of journals.

The purpose of this study is to understand stakeholders' perspectives on engagement in lupus research as participants on a lupus patient stakeholder advisory board (SAB). This study assesses SAB engagement activities, stakeholders' perspectives on engagement in lupus research, and describe potential impacts of the SAB on research projects. SAB members will provide input on a variety of lupus research studies designed at UNC. Our aim is to assess SAB participants' perspectives on engagement with lupus research and perceptions (e.g., satisfaction, trust) of their role on the SAB providing input on lupus research, including topics identified as priorities for advancing lupus research and care outcomes. With this research, we aim to increase understanding of approaches and opportunities to effectively engage patient stakeholders in lupus research. This study will also explore stakeholders' perceptions of social support, in particular any sense of community or satisfaction derived from involvement in the lupus SAB.

The purpose of this research is to assess the effectiveness and safety of cochlear implantation in children and adult patients, aged 5 years and older, with unilateral hearing loss/single-sided deafness (UHL/SSD) to support a change in indication for use.