he purpose of Parents and Infants Inter(X)action Intervention (PIXI) is to study ways of supporting the early development of infants diagnosed with rare neurogenetic disorders in their first year of life. PIXI is funded by the John Merck Fund and is led by RTI International (RTI) in collaboration with researchers at the University of North Carolina Chapel Hill. The team includes neurodevelopmental psychologists, early interventionists, and experts in neurogenetic conditions (e.g., fragile X syndrome, Angelman syndrome), autism spectrum disorder, and early childhood development. The goal of PIXI is to provide developmental and behavioral support for infants with rare neurogenetic disorders through a two-phase targeted parent-mediated intervention program.

This Incubation Project is motivated by ethical questions around policies and practices concerning research engagement with U.S. Indigenous Peoples whose tribes are unrecognized by the federal government. The pilot study includes activities aimed at (1) elucidating their perspectives on environmental research ethics, (2) evaluating the breadth and depth of current environmental research engagements within their communities, and (3) assessing their perspectives and gathering feedback on emerging research policies.

The purpose of this research study is to understand how the monitoring of Patient-Reported Outcomes (PROs) could help improve surgical care for patients undergoing chest surgeries. PROs are symptoms directly reported by patients through the completion of a survey.

To study the use of long-acting injectable antiretroviral therapy (LAI) among a racially, economically, and geographically diverse group of persons with HIV

The aim of this questionnaire is to explore awareness, perceptions and utilisations of PPI (Patient & Public Involvement) and the barriers to its use among researchers within the Psychiatric Genomics Research community. This survey is part of ongoing work from the Psychiatric Genomics Consortium (PGC) Outreach Committee and the International Society of Psychiatric Genetics (ISPG). Data will inform the PGC Outreach Committee on how it can support PGC members in their outreach activities and will be shared at a PGC World Wide Lab 2024/2025.

The purpose of this study is to collect samples from patients with GI conditions that are coming to UNC for upper endoscopy as part of their clinical care. Samples will be stored and used for research to learn more about GI conditions.

To evaluate the safety and tolerability of ascending dose-levels of multiple intrathecal bolus (ITB) administrations of ION582 in patients with Angelman syndrome (AS) based on incidence and severity of treatmentemergent adverse events (TEAEs) and serious adverse events (SAEs), changes in vital signs and changes in clinical laboratory results.

Purpose is to evaluate the ear tube simulator and compare to actual ear tube placement in patient.

The purpose of this research study is to survey what is currently being practiced among current third/fourth year dental students at the UNC Adams School of Dentistry with regards to treatment of dental infections.

To assess the challenges and support needed to serve as a clinical champion for non-invasive ventilation in hospitals for patients with COPD