Adolescents with Disorders of Gut-Brain Interaction (DGBI) commonly have difficulties with eating. However, little is known about the degree of eating difficulties or related impact on DGBI symptoms. This study will systematically study Feeding and Eating Disorders in adolescents with DGBI. We will also collect saliva and fecal samples to initiate a biosample repository.

The purpose of this registry is to observe outcomes of heart transplant recipients who are managed with HeartCare. This is done by collecting information about your heart transplant such as test results, biopsy results, and outcomes, storing that information in a database, and using that information for research.

To gather national compensation data from behavioral science faculty who teach in family medicine residency programs.

To explore cognitive burden perceptions among physicians with relation to case report writing. To understand impact of perceived workload on case report publication rates. And to identify infrastructure and AI-driven mechanisms to reduce cognitive burden among physicians in producing case reports and increasing publication.

The goal of this study is to gather information about people with a chromosome 15 condition. The information will be linked to information from other studies in the LADDER database. Identifying information will be removed. Researchers will be able to use the information to try to improve the quality of life for people living with these conditions.

Hunter Syndrome or Mucopolysaccharidosis II (MPS II) is a rare genetic disorder caused by decreased levels of a specific enzyme, iduronate-2-sulfatase. Lack of this enzyme causes buildup of large sugar molecules called glycosaminoglycans (GAGs). The build up of GAGs causes significant damage to the body and brain. Idursulfase-IT, an enzyme replacement therapy, was developed for the treatment of patients with Hunter Syndrome with cognitive impairment to help with the central nervous system manifestations of the disease. The purpose of this post-trial access program is so that patients with Hunter syndrome who previously received monthly administration of idursulfase-IT through participation in an earlier clinical research study can continue to receive it.

The purpose of this study is to understand the ways in which systemic sclerosis (SSc) develops and identify potential treatments. Because this study focuses on the interaction between macrophages and fibroblasts, both peripheral blood and skin will be necessary for completion of this work. Results from this work will provide the rational basis for the development of novel treatments for SSc patients.

The purpose of this study is to characterize the natural history of DRPLA patients using a variety of clinical and biomarker modalities and to identify genetic factors, biomarkers, and clinical measures that could predict disease progression.

Professionalism is the first of six core competencies required in the curriculum of residency programs. Significant research has been done exploring the domains of professionalism in general and within the context of anesthesiology and anesthesiology training. Although little research has been done to identify breaches in professionalism most common today, research has shown there is a correlation between unprofessional behavior among physicians and patient dissatisfaction, lawsuits, and negative patient outcomes. The purpose of this study is to identify the most commonly perceived domains of unprofessional behavior observed in anesthesiology residency training programs. Additionally, we wish to see if professional lapses may stem from generational differences between teachers and trainees in their perception of professional behavior.

The CDC reports that more than half of STD cases occur in youth aged 15-24 years old. As such, STDs are an important public health concern. This pilot study will test a series of condom promotion messages to select the most promising messages encouraging condom use among young adults.