We are studying how giving instructions and support materials can help people use Virtual Reality Therapy (VRx). VRx is a new type of treatment that doesn't use medicine and can help with anxiety, depression, pain, and other problems. We want to learn how to make these treatments easier for people to use at home.

The purpose of this study is to determine the recommended ABBV-400 dose when ABBV-400 is given alone (monotherapy) in Stage 1, and to assess if ABBV-400 monotherapy is a safe and effective treatment compared to the standard of care (SOC) LONSURF [Trifluridine and Tipiracil] plus Bevacizumab in subjects with c-Met overexpressed (level of c-Met protein in your tumor cells is increased) uncontrolled metastatic colorectal cancer in Stage 2 of the study plan.

Do you have metastatic colorectal cancer? Does your cancer lack certain mutations? If so, you might be eligible to take part in a trial to look at the effects of an investigational anticancer drug given with normal therapy.

Do you identify as Malaysian? Are you a part of a religious organization in Malaysia? Are you interested in the state of gender equality in Malaysia? If so, you will be able to participate in a study on the challenges men in Malaysia face when involved in gender equality work. We will also explore people's opinions on their involvement. Compensation provided.

In patients undergoing rotator cuff tear repair surgery, there is a correlation between poor psychological function before surgery and worsening of post-intervention outcomes, such as persistence of postoperative pain intensity and worse levels of function/disability. There is a need to address these poor responses prior to and after surgery to improve outcomes. Psychological skills training is a component of psychologically informed practice, which encompasses managing emotions, building confidence, goal-setting, enhancing motivation, and addressing injury-related fear. It is unknown if psychological skills training is a feasible and acceptable way to address these unfavorable responses after rotator cuff repair surgery. Prior to conducting large clinical trials assessing the efficacy of psychological skills training interventions, a proof of concept study is needed to determine if patients find psychological skills training as feasible, acceptable, and appropriate during their recovery from rotator cuff repair surgery.

Do you suffer from fibromyalgia? Do you have chronic widespread pain? If so, you may be able to participate in a research study to find out if certain types of light can help with your pain severity and sensitivity. Compensation provided.

If you have Polycythemia Vera and are experiencing complications, you may be eligible to participate in a research study testing the safety of a new drug called GIVinostat.

Do you spend a large portion of your day sitting? Do you exercise less than 90 minutes per week? If so, you may be able to take part in a study looking at how sitting and movement affect your life. We want to help lower the chances of getting heart disease and diabetes. Compensation provided.

We are conducting a research study to evaluate sleep and psychological outcomes in individuals 1-month to 3-months post-ACLR. This will help identify changes after ACLR to help develop future interventions to improve outcomes after ACLR.

Do you have recurring Chronic Lymphocytic Leukemia? If so, you may be able to take part in a study on two medicines to treat patients whose chronic lymphocytic leukemia has come back. We will also check if this treatment is safe for treatment.