The purpose of this study is to explore etentamig (ABBV-383) and its safety and tolerability as a monotherapy or combined with other anti-myeloma agents. This study aims to determine the safest dose of etentamig and if it produces meaningful anti-myeloma activity for participant with multiple myeloma (MM).

Pleuropulmonary Blastoma (PPB) is a rare lung tumor in young children that can grow in stages from less serious (Type I) to more dangerous (Type III). This study will test how well a drug combo: vincristine, topotecan, and cyclophosphamide (VTC) works for serious types (Type II and III) and help decide which patients with less serious tumors (Type I and Type Ir (regressed) PPB ) need chemotherapy after surgery. Researchers will also study the biology of the tumor to learn more about it.

The purpose of this single-arm phase 2 study is to evaluate the efficacy of digoxin in treating relapsed non-SHH, non-WNT medulloblastoma in pediatric and young adult patients.

This study seeks to better understand the unmet needs and care preferences of young adult cancer patients and their caregivers. Interviews to gather this information will be used to tailor an existing, evidence-based patient navigation program to these needs and preferences.

The main goal of this project is to create an interactive online version of the Let's Talk program and test it with patients who have Lynch syndrome to see if it works well in a medical setting.

The purpose of this protocol addendum is to provide participants from Study LOXO-NGR-21001 (J3T-OX-JZTA), who continue to receive benefit from LOXO-260, the opportunity for continued access to LOXO-260.

The purpose of this study is to assess how the use of community health-workers for human papillomavirus (HPV) testing influences the number of women living with HIV who get screened for cervical cancer.

Ovarian cancer is the second most frequently diagnosed gynecologic cancer in the United States. Although it is the eleventh most common cancer among women, ovarian cancer is the fifth leading cause of cancer-related death. Fortunately, survival rates for ovarian cancer patients have been improving over the past few decades due to advances in medical procedures and the availability of new cancer drugs. However, studies have shown that the improvement of clinical outcomes are unequal among patients of different racial and ethnic backgrounds. This study seeks to understand the factors associated with healthcare disparities in Black ovarian cancer patients and identify features of programs that have been successful in addressing these racial imbalances. The findings of this study will help the researcher develop future programs to address healthcare disparities in Black ovarian cancer patients.

We want to learn more about how patients who have small renal masses make treatment decision and about what kinds of features they value in the tests that we use to work up this condition.

The goal of this study is to assess the feasibility of a nutrition program for individuals with cancer who are undergoing treatment. The nutrition program includes counseling from a registered dietitian, food logging, and nutrition symptom tracking.