To compare the prevalence, severity, and timing of chronic health conditions (CHC) in a cohort of patients with DS-AL (Down Syndrome Acute Leukemia) with age-comparable DS individuals that have no cancer history. Our secondary objectives will compare NP (Neuro-Psychological) and health-related quality of life outcomes in survivors of DS-AL compared with age-comparable DS individuals with no cancer history, and will identify risk determinants of CHC and NP late effects among survivors of DS-AL.
This study is being conduced to assess the feasibility of conducting multi-center prospective studies on surgical excision of suspected OSSN lesions in SSA in people living with HIV/AIDS (PLWHA).
The overall objective of this project is to examine differences in performance fatigability and contributing mechanisms between firefighters in cancer remission and healthy firefighter controls. Findings from this research project will inform future interventions to reduce CRF in firefighters in cancer remission.
The goal of this study is to assess the feasibility of a nutrition program for individuals with cancer who are undergoing treatment. The nutrition program includes counseling from a registered dietitian, food logging, and nutrition symptom tracking.
To evaluate the safety and effectiveness of the GPX® Embolic Device when used as indicated for embolization procedures, procedures to stop blood flow to certain tumors.
The purpose of this study is to assess how the use of community health-workers for human papillomavirus (HPV) testing influences the number of women living with HIV who get screened for cervical cancer.
The purpose of the study is to determine whether the continuing detection of cell-free plasma tumor DNA (ptDNA), circulating tumor cells (CTCs), and cytokines (chemicals that help the immune system communicate) in the blood can help to better evaluate the status of a patients cancer over the course of therapy.
The purpose of this study is to explore etentamig (ABBV-383) and its safety and tolerability as a monotherapy or combined with other anti-myeloma agents. This study aims to determine the safest dose of etentamig and if it produces meaningful anti-myeloma activity for participant with multiple myeloma (MM).
The purpose of the DETECT study is to learn more about how some breast tissue features show up on a mammogram and what these features can tell us about the potential for a breast cancer diagnosis. Your participation will help us understand how the appearance of those breast tissue features is affected by hormone levels. Our objective is to collect urine samples that we will use to measure hormone levels. We will examine how hormone levels are related to breast tissue features measured from a breast cancer screening mammogram.
This study seeks to understand how best to increase knowledge about clinical trials, best way of communicating information about clinical trials, and suggestions for improving clinical trial participation particularly among African Americans (AA).