Did you know that over 250 million persons are affected by Osteoarthritis? It is the leading cause of disability among adults and has no cure. Prevention of OA is preferable to treatment and females are affected at nearly twice the rate as males. If you are a female, at least 50 years of age, overweight, with no or occasional knee pain, you may be able to participate in a research study to find out if a diet and exercise program or a health education program prevent knee OA.

Did you have head or neck cancer? Have you completed radiation in the past 3 years or more and now have dry mouth? You may be able to take part in a research study to help us learn if a gene therapy can help people with dry mouth due to radiation therapy.

Do you have grade 1 or 2 edometrioid endometrial cancer? You may be able to take part in a study to learn more about and test a new drug.

Have you been diagnosed with high-risk early triple-negative breast cancer (TNBC) without mutations in the BRCA1 or BRCA2 gene? If you still have evidence of TNBC in your breast or lymph node tissue after receiving treatment and surgery, you may qualify for this clinical research study. This study will test an experimental drug combination to find out which treatment is better at delaying the return of cancer.

Are you scheduled for weight loss surgery within the next 12 months? You may be able to take part in a research study to help us learn more about your metabolic hormones, eating behaviors, stress, and weight loss before and after your surgery.

The goal of this study is to create a support group and resources for adolescents who identify as both autistic and gender diverse using input from adolescents, parents, and professionals.

Do you have Cutaneous Lupus Erythematosus (CLE)? If you have tried antimalarials but they haven't helped your skin get better, you may be able to take part in a research study. In this study, we want to find out if a new drug improves the skin of patients with CLE. Compensation provided.

In this study, we want to learn more about two strategies that interrupt sitting: walking and seated pedaling. Sitting, or sedentary behavior, is a public health crisis that increases all causes of mortality and doubles the risk of cardiovascular disease. Interrupting sitting may help reduce the cardiovascular disease risk associated with uninterrupted bouts of sitting.

Nutrition is not one-size-fits-all. Nutrition, or the foods we eat, can help prevent and fight conditions such as high blood pressure, diabetes, stroke, and more. However, we all live in different environments, we come from different cultures, and each of us is starting from a different place with our health. Additionally, everyone breaks down food differently. Join the Nutrition for Precision Health research study to help researchers learn how our genes, cultural backgrounds, and environments affect our bodies' responses to food. Compensation provided.

Have you been diagnosed with cancer and either your cancer did not respond to treatment or your cancer progressed? If so, you may be able to take part in a research study evaluating the safety of an investigational treatment called LOXO-435 in cancer patients.