The purpose of this study is to investigate the effects of using durvalumab plus platinum doublet chemotherapy (carboplatin/abraxane or carboplatin/pemetrexed) with or without abequolixron (RGX-104) in patients with non-small cell lung cancer (NSCLC) before surgery.

In this study, we want to learn more about the safety and effectiveness of using a personalized vaccine with a drug called pembrolizumab for the treatment of non‐small cell lung cancer (NSCLC) and squamous cell cancer of the head and neck (SCCHN).

People with SCLC are usually treated with a combination of drugs that are approved by the Food and Drug Administration (FDA). However, these drugs may no longer be working in controlling your cancer or may not be a good treatment option for you. This study uses an investigational combination of drugs, trilaciclib and lurbinectedin. The purpose of this study is to test whether trilaciclib helps minimize the side effects of lurbinectedin and therefore improve the safety of lurbinectedin for the treatment of small cell lung cancer (SCLC).

People with Parkinson disease often develop difficulty walking. Metronomes are thought to help improve walking. We believe that setting metronomes slower while walking on a treadmill and faster when walking over the ground may target certain portions of gait. Our goal is to create beneficial changes in the way that people walk that persist and can be seen in the long-term.

This is a research study to investigate how collecting information about treatment-related side effects directly from patients can help manage the side effects associated with certain oral chemotherapies in patients with metastatic renal cell carcinoma.

Have you been diagnosed with Leukemia and looking for another treatment option? Do you have Myelofibrosis (MF), myelodysplastic syndrome (MDS) and /or myelodysplastic/myeloproliferative overlap syndrome (MDS/MPN)? You may be able to take part in this study to find out the safety and effectiveness of a study drug.

In this study, we want to find out more about how adults learn a second language, specifically how native speakers of America English learn Russian.

The purpose of this study is to see whether an infusion of stem cells improves lupus disease activity when compared with a placebo infusion. Other studies have shown that stem cells help reduce inflammation and are thought to be safe. This study will help confirm whether this is an effective and safe treatment for lupus.

Are you a woman aged 65 years or older with early stage breast cancer? Have you or are you scheduled to receive a lumpectomy? If so you may be able to take part in a clinical trial to measure quality of life after breast cancer treatment.

In this study, we want to learn if existing services meet the needs of people who experience crime in North Carolina. Specifically, we will focus on whether these services meet the needs of crime victims from historically underserved populations. We also want to learn whether service accessibility is different across the state. Although the assessment is meant to cover all North Carolinians, the GCC and research team have identified specific priority populations, including: veterans, immigrants, refugees, people with disabilities, older adults, LGBTQ+ individuals, teens, people from religious minority groups, people who are unhoused/experiencing homelessness, co-victims of homicide, indigenous communities, people with limited English proficiency, and people of color.