This is a Phase III study to help us improve outcomes of patients with ER+/HER2- early breast cancer with intermediate or high risk for disease recurrence. This study is for patients who have completed definitive locoregional therapy and standard adjuvant endocrine therapy for at least 2 years and up to 5 years without disease recurrence. In this study, we want to learn if a new oral "SERD" therapy called Camizestrant is helpful in reducing chance of recurrence. Talk to your Medical Oncologist for more information about this trial.

This is a research study to investigate how collecting information about treatment-related side effects directly from patients can help manage the side effects associated with certain oral chemotherapies in patients with metastatic renal cell carcinoma.

The purpose of this study is to learn more about the safety and effectiveness of the study drug (INCB057643) as monotherapy for participants with relapsed or refractory myelofibrosis.

The purpose of this study is to learn more about how to motivate survivors to get recommended health screening after their treatment is complete.

The purpose of this research study is to learn whether there are pre-treatment factors that impact quality of life and function 3 years or more after primary treatment of breast cancer. The factors we will look at in this study may include patient characteristics, specific breast cancer diagnosis, treatments, toxicities or adverse events during treatment.

If you or your child has been diagnosed with acute lymphoblastic leukemia (ALL), you or they might be able to take part in a research study. This study aims to understand why there are differences in outcomes in adolescents and young adults treated for ALL.

In this study, we want to learn more about how stress related to COVID-19 can affect behaviors and the way that genes work (epigenetics) in healthcare workers. This study focuses on healthcare workers because they are in the frontline of the pandemic.

The purpose of this study is to see whether an infusion of stem cells improves lupus disease activity when compared with a placebo infusion. Other studies have shown that stem cells help reduce inflammation and are thought to be safe. This study will help confirm whether this is an effective and safe treatment for lupus.

In this study, we want to find out more about how adults learn a second language, specifically how native speakers of America English learn Russian.

In this study, we want to learn if existing services meet the needs of people who experience crime in North Carolina. Specifically, we will focus on whether these services meet the needs of crime victims from historically underserved populations. We also want to learn whether service accessibility is different across the state. Although the assessment is meant to cover all North Carolinians, the GCC and research team have identified specific priority populations, including: veterans, immigrants, refugees, people with disabilities, older adults, LGBTQ+ individuals, teens, people from religious minority groups, people who are unhoused/experiencing homelessness, co-victims of homicide, indigenous communities, people with limited English proficiency, and people of color.