In this study, we want to learn more about the safety and tolerability of a drug called NX-1607 in adult patients with advanced tumors. We want to see if this new drug may be able to slow the growth of your cancer.
In this study, we will learn more about the safety and effectiveness of a study treatment that is injected into one of the kidneys of patients with Chronic Kidney Disease and Type 2 Diabetes.
Have you been diagnosed with an advanced cancer that has not responded to or has stopped responding to treatment? Have you had genetic testing done on your cancer? If so you may be able to take park in a research study to observe how certain cancer drugs target tumor DNA. Travel reimbursement provided.
Have you been diagnosed with cervical cancer? If so, you may be able to take part in a research study that aims to identify a new non-invasive biomarker (blood test) to 1) detect cervical cancer during screenings and 2) track response to treatment, detect early recurrence and guide personalized treatment decisions. In this study we will measure levels of Circulating Tumor Human Papilloma Virus DNA (ctHPVDNA) levels in the blood and urine of women with newly diagnosed cervical cancer prior to receiving any treatment, and then compare this to the levels in samples collected after treatment (surgery of chemoradiation).
Have you been diagnosed with Pancreatic Cancer. If so, you may be able to take part in a research study looking at the safety of giving a drug called CA-4948 Added to Standard Chemotherapy to Treat Metastatic or Unresectable Pancreatic Cancer
People with Barrett's esophagus are at higher than average risk of developing esophageal cancer. Obeticholic Acid (OCA) is a medication similar to bile acids (a fluid made and released by the liver). OCA binds to a group of cells in the intestine that is believed to have a positive effect on preventing cancer development. The purpose of this study is to compare the safety and effects of OCA with that of a placebo on the risk of developing esophageal cancer in people with Barrett's esophagus.
This is a research study for people diagnosed with AML. The purpose of this study is to see if the treatment of a combination of two drugs (cytarabine liposome therapy) and adding a third drug (pomalidomide) in different doses is more effective.
This is a study for people with colon, pancreatic, Squamous Non-small cell lung cancer, or Squamous cell carcinoma of head and neck. In this study, we want to find out if an investigational drug (Tisotumab Vedotin) is effective for people with solid tumors.
This is a Phase 2 clinical trial to test the response of the drug combination of ZEN003694 and Talazoparib. In this study, we want to learn whether this combination works to slow the growth of cancer.
The study aims at finding how much skin should be removed around the melanoma. Currently, doctors do not know how much skin to remove from around a melanoma to reduce the chances of the melanoma coming back. This study will help to learn if this approach is better or worse than the usual approach for melanoma surgery.