People with Barrett's esophagus are at higher than average risk of developing esophageal cancer. Obeticholic Acid (OCA) is a medication similar to bile acids (a fluid made and released by the liver). OCA binds to a group of cells in the intestine that is believed to have a positive effect on preventing cancer development. The purpose of this study is to compare the safety and effects of OCA with that of a placebo on the risk of developing esophageal cancer in people with Barrett's esophagus.

The purpose of this study is to test the safety of a drug called CA-4948 in combination with gemcitabine and nab-paclitaxel. Gemcitabine and nab-paclitaxel have already been approved by the FDA to be given through a vein in your arm. This study tests different doses of the drug CA-4948 to see which dose is safer for people. There will be about 36 people taking part in this study.

Do you have head and neck cancer or soft tissue sarcoma? Are you planning to have surgery to remove your tumor? You may be able to participate in a research study to determine which therapies may be best for future patients. Compensation provided.

In this study, we want to learn how we can increase awareness and availability of specialty pain care services for Black men. We will do this by asking questions about physical health, access to health care, decision-making, and factors that impact someone's health.

In this study, we want to learn more about the impact of micro-influencers on young adults between ages 18 and 25.

This study is a survey that will provide information about college students access to birth control on different campuses. By responding to this survey you will help the research team to find out how on campus pharmacies can contribute to campus health and access to birth control.

The risk factors that drive health are unique to various patient populations and different patient populations use different language to communicate their health risk factors. The health risk factors and language that patients use also differs by locations. We are holding focus group sessions with family medicine physicians, senior patients, caregivers of senior patients, patients experiencing homelessness, and patients experiencing food insecurity to gain a deeper understanding of the major health risk factors they face and the words they use to describe them.

To see how people respond to compliments sent with emojis over text.

The purpose of this project is to quantitatively and qualitatively examine the adherence and acceptability of the Oura Ring, and to examine the accuracy of the Oura Ring to measure physical activity. *This study is a collaboration with the UNC Sports Medicine Institute*

In the Carolina Blue Project, we want to learn more about work-related stress, eating behaviors, and cardiovascular disease risk factors among law enforcement officers. If you work as a law enforcement officer in any North Carolina or nearby states law enforcement department, you may be able to take part in this study. We do not collect any personally identifiable information. Officers who participate in the project and complete the two required steps will receive a $100 Amazon gift card.