We are researching the genetics of those who have major depressive disorder or bipolar disorder and have received or been evaluated for interventional treatments such as ECT (Electroconvulsive Therapy), TMS (transcranial magnetic stimulation), esketamine, and ketamine. "GenECT" is a research study to find ways to improve treatment for severe depression. We want to answer questions like: "Why do some people get severe depression and other people do not?" "Why do interventional treatments like ECT benefit some people more than others?" The GenECT study is a global effort to understand the genetics of severe depression. Dozens of doctors and scientists from around the world are working together with tens of thousands of patients to find out the answers to these questions. UNC is a lead site in this global effort.

Are you a healthy person? Have you wanted to get involved in clinical research in lung diseases? If so, you can join our registry list of interested individuals through a quick online form. We will give you a call if there are studies that you may be eligible for.

To collect cells from the nose and blood of humans to perform various experiments

Do you have mantle cell lymphoma or other non-Hodgkin lymphoma that has either come back or did not get better with your last treatment? If so, you may be able to take part in a study that will modify your own immune cells to see if it may treat your cancer.

Much of autism research has been conducted with males. We want to learn more about the experiences of females with autism and their families. This research will help us to tailor future research studies toward autistic females.

Have you been diagnosed with primary central nervous system (CNS) lymphoma? If so you may be able to take part in a research study looking at whether using the study drugs lenalidomide, and nivolumab can be safely used in addition to the standard treatment of primary CNS lymphoma, and which dose is the most adequate when they are used together.

The purpose of this study is to hear the experiences of LGBTQ+ EMS providers on the job. We want to learn more about the emotional, mental, and physical effects of identifying as LGBTQ+ in EMS.

For caregivers of grieving children who weren't the romantic partner of the parent who died (if you weren't together as a couple) at the time of their death, please help us better understand your experience. Sharing your thoughts will help us create better resources and support for families like yours.

The purpose of this study is to test whether giving the study drug acalabrutinib is safe and could help control B-cell Non-Hodgkin CNS lymphoma that have not gone away, or have come back, after the first round of treatment.

To understand the current health and well-being of athletes during the COVID-19 pandemic.