This is a non-interventional, observational study to collect data on survival, quality of life, and other follow-up information on patients who receive GammaTile therapy.
We are collecting cerebral spinal fluid (CSF) from Normal Pressure Hydrocephaly (NPH) patients to generate a biosample research repository. This repository will be used to research CSF biomarkers for Alzheimer's disease that may enhance our ability to detect and monitor Alzheimer's disease diagnoses and progression.
The purpose of this research study is to use electroencephalography (EEG) to refine our understanding of the neural mechanisms that give rise to the memory changes observed in mild cognitive impairment (MCI). The information we learn from doing this study may help improve diagnosis of MCI in the future.
The purpose of this single-arm phase 2 study is to evaluate the efficacy of digoxin in treating relapsed non-SHH, non-WNT medulloblastoma in pediatric and young adult patients.
We are no longer recruiting for this study. With the participants we do have, we obtain MRI images of the child's brain and administer cognitive behavioral assessments every 2 years. We are looking at brain structure, along with the assessments, to hopefully find biomarkers that predict mental illness.
The purpose of this study is to: 1) Examine the benefit of provider directed active rehabilitation therapies ("Active Rehab") to supplement the progressive return to activity therapies in accelerating return to duty and improving cognitive and functional limitations following mTBI, and 2) operationalize and disseminate a clinical active rehabilitation algorithm for use in military settings
This study will evaluate the safety profile of the investigational gene therapy, NGN-401, in female children with typical Rett syndrome.
The purpose of the study is to identify certain processes following brain injury that may be associated with the risk of developing epilepsy.
The purpose of this study is to test the safety and effectiveness of the drug: IMVT-1402.
Dravet syndrome is a severe form of epilepsy (a brain disorder that causes seizures). There are several types of therapies available to help reduce the number of seizures. However, even with treatment using current anti-seizure therapies, the number of seizures may not be reduced enough, and seizures may still happen.