This study is taking place to create a first-year-of-life, MRI-based predictive test for later autism spectrum disorder (ASD) diagnosis. Subjects will travel to UNC to be assessed using MRI as well as behavioral assessments and observations at 6, 12 and 24 months of age. We will also collect information about the subject's family to gather data on their environment.

To evaluate whether early drug treatment extends overall survival compared with delayed drug treatment with high-risk (chronic lymphocytic leukemia [CLL] newly diagnosed asymptomatic CLL/SLL patients.

1. Are you 18 years of age or older? 2. Have you been diagnosed with a blood clot in the past? (more than 3 months ago) 2. Do you have leg heaviness, fatigue, swelling, aching or pain? If you answered all three questions "YES" then you might be a perfect fit for the C-TRACT study.

In this study, we want to learn more about mental health stigma and mental health history. We also would like to learn about how these factors affect a person's willingness to participate in therapy.

We are doing this study to learn about the experiences of patients who have visited their primary care doctor (UNC Health affiliated clinics/providers) during the COVID-19 pandemic. With the increase in telehealth visits during the pandemic, we want to learn about your experiences! UNC-CH is a partner site for this research with Weill Cornell University. A screened participant list will be sent to Weill-Cornell (primary site) to schedule and initiate interviews.

To find the safest and most tolerable dose of CAR.B7-H3 T cells to administer in patients with relapsed/refractory platinum-resistant epithelial ovarian cancer.

Immune checkpoint inhibitors (ICIs) are a type of cancer treatment that work by over-activating the immune system to find and kill cancer cells. This type of treatment can sometimes lead to side effects that look like autoimmune diseases (diseases where the immune system attacks the body). We want to collects samples and clinical data from cancer patients taking ICI therapy to understand why some patients get side effects and others don't.

Are you currently pregnant and planning to deliver at UNC? If so, you and your baby may be eligible to take part in an exciting research opportunity! The SUNBEAM study will examine factors that lead to the development of food allergies and eczema (chronic itchy skin) in young babies and toddlers. Compensation will be provided for completed study activities.

There are 3 different non-invasive devices that are used to test how stiff your arteries are. We want to learn if these devices give us similar measurements. This will allow us to compare data across different devices, which will assist with future research.

We are researching the genetics of those who have major depressive disorder or bipolar disorder and have received or been evaluated for interventional treatments such as ECT (Electroconvulsive Therapy), TMS (transcranial magnetic stimulation), esketamine, and ketamine. "GenECT" is a research study to find ways to improve treatment for severe depression. We want to answer questions like: "Why do some people get severe depression and other people do not?" "Why do interventional treatments like ECT benefit some people more than others?" The GenECT study is a global effort to understand the genetics of severe depression. Dozens of doctors and scientists from around the world are working together with tens of thousands of patients to find out the answers to these questions. UNC is a lead site in this global effort.