The purpose of this study is to identify barriers and facilitators to the implementation of integrative medical group visits (IMGV) for patients with chronic pain in safety-net healthcare settings. IMGV is one of few integrative pain management programs designed specifically for low-income populations. By understanding what it takes to make these programs successful or not, we aim to test strategies to implement IMGV widely in safety-net settings. The goal is to make integrative pain management more accessible to low-income patients.

The purpose of this study is to identify and genomically-characterize individuals with genetically unexplained neurodevelopmental disorders, such as epilepsy. The overarching goal is to provide patients with improved information about the underlying genetic basis of their disorder and illuminate novel genetically-defined treatment approaches in the future.

The purpose of this study to is assess changes in knee joint health before and after 8 weeks of physical activity participation in individuals with a history of anterior cruciate ligament reconstruction (ACLR) 6 months to 5 years ago.

The purpose of this study is to conduct interviews to hear people's thoughts and feedback on various aspects of conducting syphilis vaccine research at UNC-Chapel Hill and to ask them to complete a brief online survey after their interviews. The information that participants provide will help the clinical trial researchers to better understand what concerns people might have about syphilis vaccine research and to design clinical trials that are acceptable to potential vaccine research participants.

Have you been recently diagnosed with Diffuse Large B Cell Lymphoma? Are you over 75 years of age? If so, you may be able to take part in a research study looking at the safety of giving a new study drug CC-486 (oral azacitidine) in addition to the standard chemotherapy drug combination used to treat this disease.

The IBIS Network recently received a grant from NIH to study brain and behavior development in infants with Down Syndrome as well as non affected infants. The goal of our new study is to identify the features of Down Syndrome at an earlier age. We will be recruiting infants across all IBIS Network locations 6-months of age and younger. Travel and Compensation provided.

This study is taking place to create a first-year-of-life, MRI-based predictive test for later autism spectrum disorder (ASD) diagnosis. Subjects will travel to UNC to be assessed using MRI as well as behavioral assessments and observations at 6, 12 and 24 months of age. We will also collect information about the subject's family to gather data on their environment.

To evaluate whether early drug treatment extends overall survival compared with delayed drug treatment with high-risk (chronic lymphocytic leukemia [CLL] newly diagnosed asymptomatic CLL/SLL patients.

1. Are you 18 years of age or older? 2. Have you been diagnosed with a blood clot in the past? (more than 3 months ago) 2. Do you have leg heaviness, fatigue, swelling, aching or pain? If you answered all three questions "YES" then you might be a perfect fit for the C-TRACT study.

In this study, we want to learn more about mental health stigma and mental health history. We also would like to learn about how these factors affect a person's willingness to participate in therapy.