The purpose of this research study is to understand how a physical activity program for family members and friends can help improve their physical activity and possibly improve the symptoms of Hispanics/Latinos with osteoarthritis.

The purpose of this study is to identify and genomically-characterize individuals with genetically unexplained neurodevelopmental disorders, such as epilepsy. The overarching goal is to provide patients with improved information about the underlying genetic basis of their disorder and illuminate novel genetically-defined treatment approaches in the future.

The purpose of this study is to identify barriers and facilitators to the implementation of integrative medical group visits (IMGV) for patients with chronic pain in safety-net healthcare settings. IMGV is one of few integrative pain management programs designed specifically for low-income populations. By understanding what it takes to make these programs successful or not, we aim to test strategies to implement IMGV widely in safety-net settings. The goal is to make integrative pain management more accessible to low-income patients.

The purpose of this study to is assess changes in knee joint health before and after 8 weeks of physical activity participation in individuals with a history of anterior cruciate ligament reconstruction (ACLR) 6 months to 5 years ago.

The purpose of this study is to conduct interviews to hear people's thoughts and feedback on various aspects of conducting syphilis vaccine research at UNC-Chapel Hill and to ask them to complete a brief online survey after their interviews. The information that participants provide will help the clinical trial researchers to better understand what concerns people might have about syphilis vaccine research and to design clinical trials that are acceptable to potential vaccine research participants.

To evaluate whether early drug treatment extends overall survival compared with delayed drug treatment with high-risk (chronic lymphocytic leukemia [CLL] newly diagnosed asymptomatic CLL/SLL patients.

A team approach looking at two approved treatments for participants with Post Thrombotic Syndrome

In this study, we want to learn more about mental health stigma and mental health history. We also would like to learn about how these factors affect a person's willingness to participate in therapy.

To find the safest and most tolerable dose of CAR.B7-H3 T cells to administer in patients with relapsed/refractory platinum-resistant epithelial ovarian cancer.

Immune checkpoint inhibitors (ICIs) are a type of cancer treatment that work by over-activating the immune system to find and kill cancer cells. This type of treatment can sometimes lead to side effects that look like autoimmune diseases (diseases where the immune system attacks the body). We want to collects samples and clinical data from cancer patients taking ICI therapy to understand why some patients get side effects and others don't.