Have you been diagnosed with a blood cancer that can be treated by transplant? If so, you might be eligible to take part in a study that will compare combinations of drugs to see which combination is better at preventing graft-versus-host disease.
Have you been diagnosed with Severe Aplastic Anemia (SAA), but don't have a matched sibling donor? If so, you may be able to take part in a study to see if a bone marrow transplant from a donor that is not related can help treat your disease. Compensation provided.
Primary Objective: Demonstrate the superiority of belumosudil in combination with prednisone vs placebo in combination with prednisone in Event-Free Survival (EFS) Secondary Objective:Demonstrate the superiority of belumosudil in combination with prednisone vs placebo incombination with prednisone in modified Lee Symptom Scale (mLSS) improvement,overall ,response rate (ORR) and in the rate of corticosteroid withdrawal
Do you have AML, ALL, or MDS, and are preparing for a stem cell transplant from an unrelated donor? If so, you might be able to take part in a study to will see if a reduced dose of a drug called cyclophosphamide will still reduce your chances of developing Graft versus Host disease, but also lower your chances of side effects from the drug.