The purpose of the NC Registry for Brain Health is to establish a mailing list of people who are interested in learning about ongoing research studies in North Carolina that are designed to improve brain health and prevent conditions such as Alzheimer's disease (AD). Anyone interested in learning more about this ongoing research or to get involved in these types of studies, now or in the future, may join the NC Registry for Brain Health. Joining is easy and free! You must be 18 years of age or older to register. People with and without memory disorders are welcome.

We are collecting cerebral spinal fluid (CSF) from Normal Pressure Hydrocephaly (NPH) patients to generate a biosample research repository. This repository will be used to research CSF biomarkers for Alzheimer's disease that may enhance our ability to detect and monitor Alzheimer's disease diagnoses and progression.

The purpose of the study is to establish a Clinical Cohort (group) of research participants to examine normal cognition, mild cognitive impairment and Alzheimer's disease and related disorders (ADRD) as people get older. We will be measuring changes in your memory and the way you process information as you age. As part of the study, you will be asked to participate in yearly evaluations of your memory and health. You will have brain imagining done by Magnetic Resonance Imaging (MRI), a lumbar puncture and blood will be drawn at some visits. Also, as part of this research you must designate a "project partner." This should be someone who is familiar with your health and will be able to provide information about your health and wellbeing as appropriate.

To determine the helpfulness of using images of brain anatomy to educate patients about their cognitive disorders.

This study will gather information about patients who are taking new medicines for Alzheimer's disease. We'll keep an eye on how these patients are doing in the long run, tracking things like how they're responding to treatment, what their overall health outcomes are like, and how safe these new treatments really are when used in the real world. The goal of this study is to get a better understanding of how these therapies actually work for a diverse group of people, not just the people who usually participate in clinical trials.