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UNC-Chapel Hill Department of Neurology

25 studies match your search
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Parkinson's Disease Treatment study

Do you have moderate Parkinson's disease with motor symptoms? Are you over 45 years old? You may be able to participate in a research study to find out if a new treatment involving surgery can help with your symptoms. Compensation provided.

Age & Gender
  • 45 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Visit Location
Open

The ADD-Me Roster: a registry for those interested in brain health or Alzheimer's research

Do you have problems with your thinking or memory? Or a parent or sibling with dementia? If so, we'd like you to join this registry about the brain and Alzheimer's disease. In return for providing us with a little bit of your health history and background, we will connect you with researchers doing studies you can join, without obligation. Many studies pay a stipend and some offer a possible treatment.

Age & Gender
  • 45 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Brain, Head, Nervous System
  • Healthy Volunteer or General Population
Visit Location
100% Remote (online, phone, text)
Not currently enrolling

Multiple Sclerosis Drug Study

In this study, we want to compare a new drug for multiple sclerosis (MS) with a drug that is already being used. We want to see how the new drug works and if it might be a better option for treating MS.

Age & Gender
  • 18 years ~ 55 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Open

Phase 2b Study to Assess Efficacy and Safety of Batoclimab in Adult Participants with Active CIDP

The purpose of this study is to see if batoclimab is safe and helps people with chronic inflammatory demyelinating polyneuropathy (CIDP), an autoimmune disorder. Batoclimab is also known as IMVT-1401. Batoclimab is injected under the skin (subcutaneously) and targets the immune system.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
Open

A randomized open label trial examining the effectiveness of Ofatumumab versus current therapy on relapsing multiple sclerosis.

Are you between 18 and 45 years of age and diagnosed with multiple sclerosis, without MS relapses within the past year? Are you currently prescribed with MS medication? If so, you may be able to participate in a research study examining whether a switch to a high-efficacy medication- Ofatumumab, would work better for you than your current treatment.

Age & Gender
  • 18 years ~ 45 years
  • Male, Female, Gender Inclusive
Study Interest
  • Chronic Conditions
  • Immune System/Infections
Open

Parkinson's Disease Genetic Registry

Have you or a family member been diagnosed with Parkinson's Disease? Would you be interested in helping researchers learn more about Parkinson's by giving a blood or saliva sample? If so, you may be eligible to participate in a research study that will utilize genetic testing to provide you more information about the possible roles of your genes in your diagnosis.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Brain, Head, Nervous System
  • Genetics and Genetic Disorders
  • Movement
Not currently enrolling

Non-invasive brain stimulation for Parkinson's non-motor symptoms

In this study, we want to understand whether we can use non-invasive brain stimulation to treat non-moto symptoms like autonomic nervous system dysfunction and depression in people with Parkinson's disease.

Age & Gender
  • 50 years ~ 90 years
  • Male, Female, Gender Inclusive
Study Interest
  • Aging
  • Brain, Head, Nervous System
  • Mental and Emotional Health
  • and 4 more
Not currently enrolling

Genetic Determinants of Neurological and Developmental Disorders

The purpose of this study is to identify and genomically-characterize individuals with genetically unexplained neurodevelopmental disorders, such as epilepsy. The overarching goal is to provide patients with improved information about the underlying genetic basis of their disorder and illuminate novel genetically-defined treatment approaches in the future.

Age & Gender
  • 0 days ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Developmental
  • Genetics and Genetic Disorders
  • Rare Diseases
Open

DLB Consortium

Do you have probable Dementia with Lewy Bodies (DLB), Mild Cognitive Impairment with "high likelihood" DLB, or Parkinson's Disease Dementia (PDD)? You may be able to participate in an observational study to track your disease progression and promote future research.

Age & Gender
  • 40 years ~ 90 years
  • Male, Female
Study Interest
  • Brain, Head, Nervous System
  • Mental and Emotional Health
By physician referral or invitation only

ZX008 for Subjects with CDKL5 Deficiency Disorder

The purpose of this study is to test the efficacy of ZX008 for kids and adults with CDD. We will measure this based on a decrease in motor seizures and using the Clinical Global Impression- Improvement rating scale.

Age & Gender
  • 2 years ~ 35 years
  • Male, Female, Gender Inclusive
Study Interest
  • Genetics and Genetic Disorders
Visit Location
100% Remote (online, phone, text)
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