Have you been diagnosed with HER2 positive (HER2+) breast cancer and have recently or plan to undergo surgery? If so, you may be able to take part in a research study looking at the safety of giving two drugs trastuzumab and pertuzumab in combination with hormonal therapy after surgery for your breast cancer.
During puberty, adolescents grow and change a lot which may make life seem more stressful and emotional. Male and female adolescents experience the changes associated with puberty differently, possibly because of different responses to changes in hormones, including testosterone and estrogen. We are interested in learning more about the role of these hormones in regulating emotional processing and mood symptoms, and whether a mobile training program can help improve mood during the pubertal transition. Participation is 8 weeks with two monthly follow-up surveys. Compensation provided.
Are you an elderly patient with locally advanced Head and Neck squamous cell carcinoma who is ineligible for standard treatment involving platinum based therapy (e.g. Carboplatin or Cisplatin)? If so, you may be eligible to participate in a clinical research study involving an investigational drug, called NBTXR3.
We are conducting a research study to use graded exposure and mobile mindfulness meditation to address clinical outcomes in individuals 6-months to 10-years post-ACLR. This will help develop effective treatments to improve outcomes after ACLR. This study will last 5 weeks. Compensation provided.
Have you been diagnosed with Low Risk Breast Cancer? Have you already been treated with surgery? If so, you may be able to take part in a research study looking at the effect of regional nodal radiotherapy.
If you or your child had or currently have abnormal cell growth or a related condition, including brain and nervous system tumors, you may be able to take part in a research study. This is a study for patients who are receiving treatment at UNC hospitals. In this study, we will collect samples to better understand the causes of your disease.
Do you have small cell lung cancer (SCLC) or non-small cell lung cancer (NSCLC)? Has your lung cancer come back or did not get better with the last treatment you were given? If so, you may be able to take part in a gene therapy research study that uses your own modified immune cells as treatment.
Are you 16 years and older, have Eosinophilic Esophagitis, have tried other therapies but they have not worked, and you have had multiple dilations for narrowing in your throat in the past 12 months? If you meet these criteria then you may be eligible for a study investigating the use of dupilumab to treat EoE patients with severe strictures. Compensation provided.
Have you been diagnosed with relapsed or refractory multiple myeloma? If so, you may be able to take part in a research study looking at the safety of giving a new drug to patients with multiple myeloma.
Have you been diagnosed with triple negative breast cancer? If so, you may be able to take part in a research study looking at the safety of giving a new drug called Sacituzumab Govitecan with or without a drug called Pembrolizumab to patients with PDL-1-negative metastatic triple negative breast cancer.