People with kidney disease that have the APOL1 risk variant are at a greater risk for developing protein in their urine and chronic kidney disease. This research study is being done to determine if the investigational drug, VX-147 can slow or stop the worsening of kidney function as well as target the underlying cause of kidney disease.

Have you or your child been diagnosed with type 1 diabetes during the past 12 months? Are you interested in helping researchers learn more about how to delay or prevent type 1 diabetes or how to treat type 1 diabetes? Join a registry to be notified of future opportunities to participate in type 1 diabetes research!

Want to help improve the treatment of people with chronic blood cancers? We are looking for healthy volunteers to take part in a simple blood-draw study. If you are generally healthy and are not taking blood thinners, you may be able to help improve treatment for patients with chronic blood cancers by donating a tablespoon of blood. This study aims to understand why individuals with chronic blood cancers have a high risk of blood clots as compared to healthy individuals, by comparing (1) the ability of blood to clot in a test tube and (2) changes in white blood cells that make them more likely to stick to blood vessels between healthy individuals and individuals with chronic blood cancers.

Does your child need a dental exam and cleaning? Your child may be able to take part in a research study where we explore ways of calming and reducing discomfort in children during dental exams and cleanings. Compensation will be provided.

Are you pregnant? Are you high risk? We know it is stressful to be pregnant when you are high-risk. We are trying to learn more about how different aspects of your life - including activity, diet, environment, stress level, and social support affect pregnancy outcomes. Compensation provided.

Are you currently pregnant and delivering your baby at UNC Women's Hospital? This exciting NIH-funded research study can help the investigators determine your risk of cardiovascular disease using a painless, non-invasive instrument that measures the stiffness of your arteries (also called pulse wave velocity).

Interested in participating in future research studies? Whether you have had a previous concussion(s) or not, you may be able to take part in several research study opportunities. This registry simply collects your contact information and then we will reach out if any study opportunities are available.

Have you previously received Radiofrequency Ablation (RFA) for your Barrett's Esophagus (BE)? You may be able to take part in a research study using the CryoBalloon Focal Ablation System, also called cryotherapy, a freezing treatment for the esophagus, to further treat your Barrett's Esophagus. All procedures and treatments will be part of your routine clinical care.

Have you been infected with COVID-19? Are you a solid organ transplant recipient? Have you or your child received a COVID-19 vaccine or are planning to receive one? If so, you may be eligible to participate in a research study that will assess your immune response to COVID-19 infection or vaccination over a 5 year period. We are looking for children and adults aged 7-95 years, and plan to collect blood every 2-6 months over the study period. (Compensation provided for the first year).

Do you sit too much at work or home? There is strong evidence for an association between sitting and cardiovascular diseases such as coronary heart disease and stroke. In this study, we want to identify strategies to break up sitting for long periods of time. Compensation will be provided.