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Research Studies

UNC-Chapel Hill Division of Nephrology & Hypertension

26 studies match your search
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Kidney Health Study

Do you or your child have a kidney condition and take certain meds? Join our study and help us make a difference! You'll also get paid for your time.

Age & Gender
  • 12 years ~ 80 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Open

Study on primary focal segmental glomerulosclerosis (FSGS) or minimal change disease (MCD)

Do you have protein in your urine and have had a kidney biopsy? You may be able to participate in a research study to test to see if a study drug can reduce the amount of protein in your urine.

Age & Gender
  • 16 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Open

Inaxaplin in Subjects With Proteinuric APOL1-mediated Kidney Disease

If you have protein in the urine and African descent, Hispanic or American Indian you might have a gene call APOL1 contributing kidney disease. This study will test if you have change in the gene. If you do have that change you can participate in this study .

Age & Gender
  • 18 years ~ 67 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Pressure
  • Diabetes
  • Kidneys and Liver
Not currently enrolling

IgA Nephropathy Microbiome Study

The purpose of this study is to compare diet (record of the foods you eat), gut microbiome (stool sample), and cells (blood sample) in adults with IgA Nephropathy (IgAN) and compare with adults with focal segmental glomerulosclerosis (FSGS) and adults with no history of medical problems. The information we learn by doing this study may help us understand how we might be able to target the microbiome to better understand the disease process and potentially help us develop new therapies in the future.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Healthy Volunteer or General Population
  • Kidneys and Liver
  • Microbiome
Open

VX-147

People with kidney disease that have the APOL1 risk variant are at a greater risk for developing protein in their urine and chronic kidney disease. This research study is being done to determine if the investigational drug, VX-147 can slow or stop the worsening of kidney function as well as target the underlying cause of kidney disease.

Age & Gender
  • 18 years ~ 60 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
  • Rare Diseases
Not currently enrolling

Evaluating Problematic Proteinuria in Kids (EPPIK)

This study is trying to learn more about a medication called sparsentan, and how it can help the kidneys filter protein and slow the decline of kidney function. The amount of protein found in the urine (called proteinuria) is seen as a marker of kidney function. Lowering proteinuria levels is associated with better kidney health outcomes.

Age & Gender
  • 1 years ~ 17 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
  • Rare Diseases
Open

CureGN Diabetes

We still have a lot to learn about why people develop glomerular disease and what the best medicines are to treat these diseases. Diabetes is a common, chronic illness and many people with glomerular disease also have diabetes. Currently, there is no information telling us the best ways to treat patients with both diabetes and glomerular disease, or how to counsel them about prognosis and risks for complications. This substudy of the Cure Glomerulopathy Network brings together information and laboratory specimens from patients with diabetes and glomerular disease to speed up and improve health research for their care.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
  • Rare Diseases
Open

Registry of kidney patients with monoclonal gammopathies

If you are seen at UNC and have been diagnosed with monoclonal gammopathies or amyloidosis, and the disease is affecting your kidneys, we would like your permission to access your medical record to learn about your treatments and how well they work.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Rare Diseases
Visit Location
100% Remote (online, phone, text)
Open

Comparing Two Treatments for Kidney Health

If you've had a kidney biopsy and learned you have a specific kidney condition, you might be eligible to join a three-year study. This study looks at how two medicines, when used together, might help treat your condition.

Age & Gender
  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Not currently enrolling

LIPOSORBER LA-15 system for Adult and Pediatric FSGS

To evaluate the safety and efficacy of a device removing lipids from the blood using an apheresis device in treating primary FSGS

Age & Gender
  • 5 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
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