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Research Studies

UNC-Chapel Hill Division of Nephrology & Hypertension

25 studies match your search
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CONFIDENCE

Have you been diagnosed with chronic kidney disease and type 2 diabetes? If so, you may qualify for a research study to see if two medicines help to treat kidney disease.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
  • Kidneys and Liver
  • Rare Diseases
Open

Goodpasture Disease (Anti-GBM) Research Study

Have you been hospitalized for anti-GBM disease (Goodpasture disease)? You may be able to take part in a research study to help us learn if adding a drug to your treatment could help stop inflammation faster and help protect the kidneys.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
  • Lungs and Breathing
Open

VX-147

People with kidney disease that have the APOL1 risk variant are at a greater risk for developing protein in their urine and chronic kidney disease. This research study is being done to determine if the investigational drug, VX-147 can slow or stop the worsening of kidney function as well as target the underlying cause of kidney disease.

Age & Gender
  • 18 years ~ 60 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
  • Rare Diseases
Open

Aurora VOCAL Study for Adolescents with Lupus Nephritis

You are participating in a clinical research study to investigate whether voclosporin (the study drug) added to standard treatment is able to reduce Lupus Nephritis disease activity in adolescents. This study involves 24 weeks of treatment and you will be required to follow specific instructions of the study as explained by your study doctor and team

Age & Gender
  • 12 years ~ 17 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Open

Treatment Study for Non-diabetic Chronic Kidney Disease (FIND-CKD)

Researchers are looking for a better way to treat people who have non-diabetic chronic kidney disease (non-diabetic CKD). The trial treatment, finerenone, is being developed to help people who have long lasting kidney disease, also known as chronic kidney disease (CKD). It works by blocking a certain hormone called aldosterone that causes injury and inflammation in the heart and kidney which is known to play a role in CKD. In this trial, the researchers want to learn if finerenone helps to slow down the worsening of the participants' non-diabetic CKD compared to a placebo. A placebo looks like a trial treatment but does not have any medicine in it. The trial will include about 1,580 men and women who are at least 18 years old.

Age & Gender
  • 18 years ~ 0 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Open

CureGN Diabetes

We still have a lot to learn about why people develop glomerular disease and what the best medicines are to treat these diseases. Diabetes is a common, chronic illness and many people with glomerular disease also have diabetes. Currently, there is no information telling us the best ways to treat patients with both diabetes and glomerular disease, or how to counsel them about prognosis and risks for complications. This substudy of the Cure Glomerulopathy Network brings together information and laboratory specimens from patients with diabetes and glomerular disease to speed up and improve health research for their care.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
  • Rare Diseases
Open

Ravulizumab/placebo for Lupus Nephritis or IgA Nephropathy

The study tests the safety and efficacy of a new type of drug, administered by intravenous infusion, for the treatment of lupus nephritis or IgA Nephropathy. You might be on the drug or on the placebo (no active drug ) and will help to figure out if this new drug is a good alternative or complement to existing drugs.

Age & Gender
  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Open

Registry of kidney patients with monoclonal gammopathies

If you are seen at UNC and have been diagnosed with monoclonal gammopathies or amyloidosis, and the disease is affecting your kidneys, we would like your permission to access your medical record to learn about your treatments and how well they work.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Rare Diseases
Visit Location
100% Remote (online, phone, text)
Not currently enrolling

Belimumab and Rituximab Compared to Rituximab Alone for the Treatment of Primary Membranous Nephropathy

This is a three-year research study for people with primary membranous nephropathy (primary MN). The study will test if combining belimumab and rituximab is effective in treating Primary MN.

Age & Gender
  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Not currently enrolling

LIPOSORBER LA-15 system for Adult and Pediatric FSGS

To evaluate the safety and efficacy of a device removing lipids from the blood using an apheresis device in treating primary FSGS

Age & Gender
  • 5 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
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