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UNC-Chapel Hill Division of Nephrology & Hypertension

27 studies match your search
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Comparing Two Treatments for Kidney Health

If you've had a kidney biopsy and learned you have a specific kidney condition, you might be eligible to join a three-year study. This study looks at how two medicines, when used together, might help treat your condition.

Age & Gender
  • 18 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Not currently enrolling

LIPOSORBER LA-15 system for Adult and Pediatric FSGS

To evaluate the safety and efficacy of a device removing lipids from the blood using an apheresis device in treating primary FSGS

Age & Gender
  • 5 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Not currently enrolling

ANCA vasculitis - figuring out who really needs maintenance therapy

This is a study for patients with anti-neutrophil cytoplasmic antibody (ANCA) vasculitis who are in remission after treatment. We want to learn if a special blood test can help us identify which patients could be monitored without additional immunosuppressive maintenance treatment. This study will not test new medications. We will use the same medications currently used for maintenance treatment of ANCA vasculitis.

Age & Gender
  • 18 years ~ 85 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Not currently enrolling

NEPTUNE

The purpose of this study is to learn more about three kidney diseases called nephrotic syndrome: Focal Segmental Glomerulosclerosis (FSGS), Minimal Change Disease (MCD), and Membranous Nephropathy (MN). By collecting health information and laboratory samples from individuals who have these diseases and by making this information available to researchers, we hope to gain new knowledge about these diseases and to find better treatments for them.

Age & Gender
  • 1 months ~ 79 years
  • Male, Female
Study Interest
  • Kidneys and Liver
By physician referral or invitation only

Study monitoring dialysis fistula maturation using an electronic stethoscope

The purpose of this research study is to try and teach a computer program to assess how a dialysis vascular access fistula is maturing, when it could be ready to put needles in, or when it needs to be fixed to allow it to mature better; based on the electronic stethoscope recordings.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Symptom Monitoring in Hemodialysis

This study is comparing two approaches for monitoring and addressing symptoms among adult patients with kidney failure who are treated with hemodialysis. For the first approach patients use an electronic system twice a month to report their symptoms. The system sends alerts to their medical team at the dialysis clinic about the reported symptoms and gives suggestions about how to manage them. The system also provides reports that show patients and their medical team the reported symptoms over time. For the second approach patients complete a quality of life questionnaire that includes questions about symptoms once a year. The questionnaire does not have follow-up support like alerts, symptom management guidance, or reports. In addition, researchers will talk to patients, dialysis clinic personnel, and medical providers about their experiences using the electronic symptom monitoring system to learn about how to best use patient-reported outcome measures in dialysis care.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

PediKidneyTool

To ascertain pediatric clinician preferences for risk stratification for pediatric kidney disease.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Healthy Volunteer or General Population
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Education Strategies for Vascular Access Creation in Advanced Kidney Disease

This study will compare 3 different ways to educate patients with advanced chronic kidney disease about hemodialysis vascular access.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

Studying Diabetic Kidney Disease in Kidney Biopsies

About two in five people who are undergoing a kidney biopsy have diabetes. Diabetes is a common finding in people with kidney disease, but little is known about the specific ways in which diabetes affects kidney function. The purpose of this study is to gather two groups of patients with diabetes who undergo a kidney biopsy in order to create a source of information with genetic, blood, and urine samples available, by which researchers can study how diabetes affects kidney function.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Diabetes
  • Kidneys and Liver
Visit Location
100% Remote (online, phone, text)
By physician referral or invitation only

PGNMID Daratumumab

A multi-center open-label trial evaluating the efficacy and safety of daratumumab in treatment of patients with proliferative glomerulonephritis with monoclonal immunoglobulin deposits.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Kidneys and Liver
Visit Location
100% Remote (online, phone, text)
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