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UNC-Chapel Hill Lineberger Comprehensive Cancer Center

241 studies match your search
Open

IDH-Wildtype Glioblastoma Treatment Study

Are you an adult who has just found out you have IDH-Wildtype Glioblastoma? If so, you could join a study to see if a new experimental pill called ropidoxuridine can help make treatment for this type of brain cancer better when used with radiation.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Brain and Other Nervous System)
Coming Soon

Relapsed Peripheral T-cell Lymphoma Treatment Study

In this study, we want to find out if a new drug called Soquelitinib (also known as CPI-818) can be safely given to people. We are also checking to see if it can help treat a type of cancer called relapsed peripheral T-cell lymphoma (PTCL).

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Conditions
  • Cancer (Lymphoma)
Open

A Phase 1b Study of AMG509 in Subjects w/ High-risk Biochemical Recurrence of Prostate Cancer

Have you been diagnosed with High-risk Biochemical Recurrence (BCR) of Nonmetastatic Castration-sensitive Prostate Cancer (nmCSPC)? If so, you may be able to take part in a research study evaluating the safety and tolerability of the study drug in adults with High-risk Biochemical Recurrence (BCR) of Nonmetastatic Castratio-sensitive Prostate Cancer (nmCSPC).

Age & Gender
  • 18 years ~ 99 years
  • Male
Study Interest
  • Cancer (Prostate, Phase 1 Trials (all cancers))
  • Rare Diseases
  • Men's Health
Open

Tailoring Therapy in Post-surgical Patients with Low-risk Endometrial Cancer

Do you have early-stage endometrial cancer? If so, you may be able to take part in a research study looking to find out if there are types of early-stage endometrial cancer that require less treatment than the usual approac

Age & Gender
  • 18 years ~ 99 years
  • Female
Study Interest
  • Cancer (Uterine (endometrial))
Open

Advanced Melanoma Treatment Study

Do you have advanced melanoma that has progressed on treatment? Do you have a tumor longer than 1cm in length? If so, you might be able to take part in a study that compares a study treatment (Vusolimogene Oderparepvec and Nivolumab) with your physician's choice of standard of care treatment. Compensation provided.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Melanoma)
Open

UMA-ALI-1201: A PHASE 2 STUDY OF ALISERTIB IN COMBINATION WITH ENDOCRINE THERAPY IN PATIENTS WITH HR+, HER2-NEGATIVE RECURRENT OR METASTATIC BREAST CANCER

Have you been diagnosed with hormone receptor (HR+) and human epidermal growth factor receptor 2 (HER2)-negative recurrent or metastatic breast cancer? If so, you may be eligible for a clinical trial investigating the combination of endocrine therapy with alisertib.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Breast)
Open

Rehabilitation outcomes study

Have you been diagnosed with cancer. If so, you may be able to take part in a research study looking to improve cancer care for patients whose treatment outcomes have led to challenges in their quality of life.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Bladder, Brain and Other Nervous System, Breast, and 19 more)
Open

Basal-like PDAC treated with Gemcitabine, Erlotinib and nab-paclitaxel (PANGEA).

Are you a patient with advanced basal-like pancreatic adenocarcinoma? If so this could the a Trial for you to as this is a Phase I/II trial is to evaluate the safety, efficacy and tolerability of low-dose EGFR inhibitors in combination with bi-weekly gemcitabine/nab-paclitaxel (GnP) in subjects with basal tumors

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Pancreatic)
Age & Gender
  • 18 years ~ 99 years
  • Female
Study Interest
  • Cancer (Uterine (endometrial), Ovarian)
Open

Venetoclax, MLN9708 and Dexamethasone for Relapsed or Refractory Light Chain Amyloidosis

Have you been diagnosed with relapsed or refractory light chain amyloidosis? If so, you may be able to take part in a research study looking at the safety and tolerability of giving Venetoclax, MLN9708 (ixazomib citrate) and Dexamethasone to patients with relapsed or refractory light chain amyloidosis.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Conditions
  • Cancer (Other Cancers)
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