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Research Studies

UNC-Chapel Hill Lineberger Comprehensive Cancer Center

254 studies match your search

Study of Belantamab Mafodotin With Carfilzomib, Pomalidomide, and Dexamethasone in Relapsed MM

By doing this study, we hope to learn if the combination of belantamab mafodotin, carfilzomib, pomalidomide, and dexamethasone is effective and safe when given to persons with multiple myeloma that has gotten worse and is not responding to standard drugs that are used for treating multiple myeloma, including chimeric antigen receptor T-cell therapy.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Conditions
  • Cancer (Multiple Myeloma)
Not currently enrolling

Little Cigar and Cigarillo Use Study

We are doing a study to develop effective messages for social media campaigns to reduce the use of little cigars and cigarillos by young adults.

Age & Gender
  • 18 years ~ 29 years
  • Male, Female, Gender Inclusive
Study Interest
  • Substance Use (tobacco, alcohol, opioids, etc)
Visit Location
100% Remote (online, phone, text)
Open

Relapsed and Refractory CLL, SLL, and Select Low-grade Lymphomas Treatment Study

Do you have Relapsed and Refractory CLL, SLL, or Select Low-grade Lymphomas? Have you received at least 2 or more therapies that have included BTKi and venetoclax? If so, you may be able to take part in a study on a drug called ZE50-0134 to treat patients with these conditions. We will also check if various doses of this medicine are safe for treatment.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Conditions
  • Cancer (Lymphoma)
Open

Combating Cancer-Related Fatigue: A Personalized Supportive Care Program

Have you been diagnosed with CLL or other forms of indolent lymphoma? If so this could be a good study for you to paticipate in. One of the primary goals of this study is To investigate the feasibility of the referral and engagement process in fatigue mitigation intervention for cancer-related fatigue among adults with CLL or other forms of indolent lymphoma.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lymphoma)
Open

APVO436-5201: APVO436 Phase 1b/2 Study in Patients with Newly Diagnosed acute myeloid leukemia (AML).

Have you been diagnosed with AML recently and looking for a different treatment option? You might be able to participate in this study.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Leukemia)
Not currently enrolling

Understanding How Couples Dealing With Prostate Cancer Handle Meals and Food Choices

We want to learn how couples dealing with prostate cancer handle food preparation and eating together.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Behavior
  • Eating, Nutrition, and Metabolism
  • Men's Health
  • and 2 more
Visit Location
100% Remote (online, phone, text)
Open

Comparison of Two Anticancer Drug Combinations in Colorectal Cancer

Do you have metastatic colorectal cancer? Does your cancer lack certain mutations? If so, you might be eligible to take part in a trial to look at the effects of an investigational anticancer drug given with normal therapy.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Colorectal)
Open

Study of GIVinostat and Hydroxyurea for High-Risk Polycythemia Vera

If you have Polycythemia Vera and are experiencing complications, you may be eligible to participate in a research study testing the safety of a new drug called GIVinostat.

Age & Gender
  • 18 years ~ 99 years
  • Male, Gender Inclusive
Study Interest
  • Blood Conditions
Open

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

Do you have recurring Chronic Lymphocytic Leukemia? If so, you may be able to take part in a study on two medicines to treat patients whose chronic lymphocytic leukemia has come back. We will also check if this treatment is safe for treatment.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Conditions
  • Cancer (Lymphoma)
Open

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

Do you have thyroid cancer? If so, you may be eligible to participate in a research study to see which targeted therapy will work better to prolong the time until your tumor grows or spreads, after initial treatment.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Thyroid and Other Gland/Endocrine)
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