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Research Studies

UNC-Chapel Hill Lineberger Comprehensive Cancer Center

270 studies match your search
Open

Study to Assess Change in Disease Activity and Adverse Events of Oral Venetoclax With Intravenous (IV) Obinutuzumab in Adult Participants With Recurring Chronic Lymphocytic Leukemia (CLL)

Do you have recurring Chronic Lymphocytic Leukemia? If so, you may be able to take part in a study on two medicines to treat patients whose chronic lymphocytic leukemia has come back. We will also check if this treatment is safe for treatment.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Conditions
  • Cancer (Lymphoma)
Open

Study of Targeted Therapy vs. Chemotherapy in Patients With Thyroid Cancer

Do you have thyroid cancer? If so, you may be eligible to participate in a research study to see which targeted therapy will work better to prolong the time until your tumor grows or spreads, after initial treatment.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Thyroid and Other Gland/Endocrine)
Open

S095031-178: Ivosidenib (IVO) Monotherapy and Azacitidine (AZA) Monotherapy in Patients With Hypomethylating Agent (HMA) Naive Myelodysplastic Syndromes (MDS) With an IDH1 Mutation

Join a Research Study for an Investigational MDS Treatment! Doctors are testing two study medicines for people with Myelodysplastic Syndromes (MDS) and an IDH1 mutation who haven't had certain treatments before.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Leukemia)
Open

Ultra Hypo-fractionated Adjuvant Whole Breast Radiation Therapy with Simultaneous Integrated Boost for Early-Stage Breast Cancer (H-ASSIST)

Have you been diagnosed with early-stage breast cancer or ductal carcinoma in situ (DCIS) and have undergone breast conserving surgery (lumpectomy). If so this may be the research for you!! You may be able to take part in a research study to evaluate the effects of the tumor bed boost when given at the same time (called a simultaneous integrated boost, SIB) with the WBI, as opposed to after the WBI.

Age & Gender
  • 50 years ~ 99 years
  • Female
Study Interest
  • Cancer (Breast)
  • Women's Health
Coming Soon

Study of MRTX1719 in Patients with Advanced Cancer and a Specific Genetic Change

This study is testing a new drug called MRTX1719. The main goal is to find the best dose of the drug to use in future studies. The study will also look at what side effects the drug may cause and how often they happen. Researchers will also measure how quickly the drug is absorbed into the bloodstream and how fast the body gets rid of it. Additionally, they will check how well MRTX1719 works against cancer.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female, Gender Inclusive
Study Interest
  • Cancer (Lung, Pancreatic, Phase 1 Trials (all cancers))
Not currently enrolling

Study of LY3537982 and Immunotherapy with or Without Chemotherapy for People with Non-Small Cell Lung Cancer

The purpose of this study is to see if adding LY3537982 to standard cancer treatments works better than just using the standard treatments alone for people with advanced non-small cell lung cancer (NSCLC) who have not yet been treated.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Lung)
Open

Study on How Volrustomig Works with Other Cancer Drugs for Treating Tumors

If you have non-squamous non-small cell lung cancer and are not currently in treatment, you may qualify for a clinical trial testing a new drug to treat tumors-study drug provided.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Lung)
Open

Solid Tumors Treatment Study

Do you have a solid tumor that has progressed on other treatments? Do you have at least one measurable tumor? If so, you may be able to take part in a study to improve treatment for advanced solid tumors. We are exploring how safe and effective a combination of drugs is.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Phase 1 Trials (all cancers))
Open

NETs Treatment Study

Have you been diagnosed with a neuroendocrine cancer that has not responded to other treatment options? If so then you may be eligible to participate in a study to examine the safety and effectiveness of a new cancer therapy designed to target specific neuroendocrine tumors cells.

Age & Gender
  • 18 years ~ 99 years
  • Male, Female
Study Interest
  • Cancer (Phase 1 Trials (all cancers))
Open

Severe Aplastic Anemia Treatment Study

Have you been diagnosed with Severe Aplastic Anemia (SAA), but don't have a matched sibling donor? If so, you may be able to take part in a study to see if a bone marrow transplant from a donor that is not related can help treat your disease. Compensation provided.

Age & Gender
  • 3 years ~ 75 years
  • Male, Female, Gender Inclusive
Study Interest
  • Blood Conditions
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