The purpose of this study is to examine psychological readiness by assessing attentional control and resilience and to determine if psychological readiness (i.e. attentional control and resilience) is predictive of physical readiness.

The purpose of this study is to determine if treating germinomas with chemotherapy followed by a lower dose of radiotherapy (RT) can be as effective as the current standard of care. Specifically, our primary aim is to determine whether 12 Gy whole ventricular irradiation (WVI) and 12 Gy tumor boost would maintain similar efficacy compared to ACNS1123 stratum 2 as measured by event-free survival (EFS) in eligible patients with localized primary central nervous system (CNS) germinoma who present with serum and/or CSF human chorionic gonadotropin-beta (hCGß) = 100 IU/L and normal AFP, and meet complete response (CR) or continued complete response (CCR) criteria following chemotherapy/second-look surgery (Stratum 1). We are attempting to build upon the excellent results of ACNS1123 stratum 2 by reducing the RT dose even further for patients in a CR after chemotherapy.

This study looks at the thoughts, beliefs, and reasons behind how gun owners in North Carolina store their guns when they have children, or have children who come to the location where their gun is stored. The results will help create gun safety programs that fit the needs of different communities.

We have created a workbook about Lynch Syndrome, a genetic condition that means an individual is at high risk of developing certain cancers, and family testing. It is important that patients with Lynch Syndrome tell their family members about their condition so their family members understand their risks and can be tested for Lynch Syndrome too. We are testing our workbook with a small group of patients with Lynch Syndrome to understand if the workbook is helpful in managing their condition and talking to family members.

The purpose of this single-arm phase 2 study is to evaluate the efficacy of digoxin in treating relapsed non-SHH, non-WNT medulloblastoma in pediatric and young adult patients.

To what extent does the unequal distribution of local wealth explain disparities in social outcomes (education, health, upward mobility)? How do individuals think that inequality around them impacts their own lives? This study aims to provide explorative evidence on people's reasoning.

This study explores the response of the adjacent gum tissue to a type of dental filling material.

To test an intervention for healthcare providers that combines provider education and patient resources to increase referrals to an arthritis management program

In this research study, we want to learn more about using DNA sequencing for individuals with severe mental illness. This may give clues about health risks now and in the future. You are being asked to participate in this research study because DNA sequencing may improve our understanding of schizophrenia, and what may be causing the type of illness that you have.

Findings from this project will identify urgently needed strategies for improving school-based mental health supports for adolescents with suicidal thoughts and behaviors to prevent suicide during resurgences of COVID-19 that force school closures.