Have you been diagnosed with Metastatic Castration-Resistant Prostate Cancer (mCRPC)? If so, you may be able to take part in a research study investigating if the study drug together with standard of care drug are safe and well tolerated, and whether two drugs are effective in treating prostate cancer, in comparison with standard of care alone.
The purpose of this study is to learn about the effects of a research investigational product, CT-0525, and to see if CT-0525 is safe for participants with advanced cancer. This study is the first time that CT-0525 will be given to humans. CT-0525 is a special kind of product that is made of blood cells taken from your own body. Once collected, these blood cells will be altered and infused back into your body.
Primary Objective: Demonstrate the superiority of belumosudil in combination with prednisone vs placebo in combination with prednisone in Event-Free Survival (EFS) Secondary Objective:Demonstrate the superiority of belumosudil in combination with prednisone vs placebo incombination with prednisone in modified Lee Symptom Scale (mLSS) improvement,overall ,response rate (ORR) and in the rate of corticosteroid withdrawal
Are you premenopausal and have been diagnosed with ER-positive, HER2-negative breast cancer and had surgery for your breast cancer? If so, you may be able to take part in a research study evaluating the addition of chemotherapy given after breast surgery with ovarian suppression and endocrine therapy versus ovarian suppression and endocrine therapy alone.
The survey and its findings will help us understand attitudes around cancer family history and genetic testing among Black people. This information will be used to develop an educational curriculum to strive towards health equity for Black people diagnosed with or at higher risk of cancer and get Black people the best cancer care.
Have you been diagnosed with Lateralized Oropharyngeal Cancer . If so, you may be able to take part in a research study looking at the safety by using a special imaging study called lymph node mapping (lymphatic mapping) Single Photon Emission Computed Tomography (SPECT-CT) compared to the usual treatment when radiotherapy is given .
Do you have AML, ALL, or MDS, and are preparing for a stem cell transplant from an unrelated donor? If so, you might be able to take part in a study to will see if a reduced dose of a drug called cyclophosphamide will still reduce your chances of developing Graft versus Host disease, but also lower your chances of side effects from the drug.
This study will evaluate the feasibility of using capillary blood samples collected with the Tasso device for analysis of CBC in diseased patients with leukemia, lymphoma, and/or other blood cell disorders.
Do you have pancreatic ductal adenocarcinoma that has come back after receiving standard therapy? If so, you may be able to participate in this gene therapy research study to learn more about using you own modified immune cells as possible treatment.
The purpose of this research study is to learn more about the risk of severe and fatal infusion-related reactions (IRR) in patients with multiple myeloma who are treated with their first 3 administrations of daratumumab. Examples of severe IRR include lung tightness, low oxygen levels, difficulty breathing, high blood pressure, racing heart, headache, and too much fluid in the lungs. No fatal IRRs have been observed in clinical trials of daratumumab. We are also doing this study to help us to identify potential risk factors for IRR.