The current study seeks to understand FLE self-care practices and develop a comprehensive framework that FLEs can utilize to initiate and maintain effective self-care routines. This is particularly important given the demanding nature of their work, which involves supporting families and individuals through various life challenges and transitions

The purpose is to evaluate coagulation activation and the impact of iron status in patients with Hereditary Hemorrhagic Telangiectasia (HHT). Participants on this study will include patients with HHT, patients with iron deficiency +/- anemia but without HHT, and healthy volunteers The study team will procure single and/or serial blood samples from participants and assess various markers of hemostasis and activation of coagulation, and host iron status.

This study is exploring the effect of clear aligner treatment on microplastics exposure and physiological uptake by collecting saliva and urine samples. Microplastic size, makeup, and quantity will be assessed before and after treatment with clear aligners.

The purpose of this study is to test a resilience program compared to a physical activity program on change in early childhood education staff's mental health and well-being.

The purpose of this study is to estimate the number of Lyme and other tick-borne disease cases occurring in Biltmore Forest.

The goal of the study it to see how well NTM infection in cystic fibrosis patients responds to phage therapy.

The purpose of this study is to determine if treating germinomas with chemotherapy followed by a lower dose of radiotherapy (RT) can be as effective as the current standard of care. Specifically, our primary aim is to determine whether 12 Gy whole ventricular irradiation (WVI) and 12 Gy tumor boost would maintain similar efficacy compared to ACNS1123 stratum 2 as measured by event-free survival (EFS) in eligible patients with localized primary central nervous system (CNS) germinoma who present with serum and/or CSF human chorionic gonadotropin-beta (hCGß) = 100 IU/L and normal AFP, and meet complete response (CR) or continued complete response (CCR) criteria following chemotherapy/second-look surgery (Stratum 1). We are attempting to build upon the excellent results of ACNS1123 stratum 2 by reducing the RT dose even further for patients in a CR after chemotherapy.

This study looks at the thoughts, beliefs, and reasons behind how gun owners in North Carolina store their guns when they have children, or have children who come to the location where their gun is stored. The results will help create gun safety programs that fit the needs of different communities.

The purpose of this single-arm phase 2 study is to evaluate the efficacy of digoxin in treating relapsed non-SHH, non-WNT medulloblastoma in pediatric and young adult patients.

To test an intervention for healthcare providers that combines provider education and patient resources to increase referrals to an arthritis management program