The purpose of this protocol addendum is to provide participants from Study LOXO-NGR-21001 (J3T-OX-JZTA), who continue to receive benefit from LOXO-260, the opportunity for continued access to LOXO-260.

This study looks at the thoughts, beliefs, and reasons behind how gun owners in North Carolina store their guns when they have children, or have children who come to the location where their gun is stored. The results will help create gun safety programs that fit the needs of different communities.

We are asking people about their first experience paying for lactation consultant support and/or double electric breast pumps and other lactation supplies once home from the hospital. We want to understand how the cost of lactation support is impacting people meeting their lactation goals.

The goal of this study is to look into the patient-reported and functional outcomes of patients who have undergone total femoral replacement or osseointegrated amputation for oncologic and traumatic indications. We want to see if functional and patient-reported outcomes are correlated and if patient satisfaction with the implants differs between surgical indications.

We are conducting this study to see how well athletes with blood clots are able to manage their blood thinner around training and competition.

As machine learning is accepted as one of the most powerful tools to solve problems that involve a large amount of data, more and more application areas started to explore and adopt machine learning methods into their workflows. The first step of developing a machine learning model is to determine the target variable, i.e. what to predict. For instance, if a practitioner wants to develop a model to assist hiring decisions, he/she may choose a candidate's performance score as the prediction target to train the machine learning model. In practice, practitioners need to experiment and evaluate a large set of potential target variables until they reach a satisfactory one. We would like to automate the evaluation of target variables and recommend good ones to the users. The purpose of this study is to understand how different recommendation strategies influence the target selection process.

To evaluate the effect of mitapivat on albumin creatinine ratio (ACR) response in subjects with sickle cell disease (SCD) and nephropathy

The study team made a survey to assess what medical residents in OBGYN, Family Medicine, and Emergency Medicine programs across North Carolina know about expedited partner therapy. The survey also looks at the challenges and helpful factors related to using this therapy.

We want to develop a registry of patients with Stevens-Johnson Syndrome and Toxic Epidermal Necrolysis who attend the UNC Department of Ophthalmolgy,

The primary purpose of this research is to share insights gained from developing and teaching a new, multi-campus course. We ask: what are the unique contributions and challenges of developing a cross-campus, collaborative learning model for teaching planning and equity related topics? How and why did the zoning for equity collaborative learning model evolve over time? What are the lessons learned and takeaways from such a pedagogical innovation? We answer these questions by analyzing the following data: archived course materials and anonymous student evaluations, transcripts of the guided discussions among faculty who developed and offered the course, and transcripts of the interviews of former-students who took the class.