This is a longitudinal cohort study with a concurrent mixed-methods design to determine the interrelationship between how stroke survivors adapt to and longitudinal changes in fatigue and recovery of physical function within 6 months poststroke (during index hospitalization, 1, 3, and 6 months).

This study will be the first to investigate potential linkages between early life adversity, parenting quality, child self-regulation, and biological aging during the critical period in early childhood when telomeres are eroding most rapidly and may be most susceptible to environmental input. The long-term goal is to determine how early adversity becomes biologically embedded in early childhood in order to prevent or mitigate risk to later health and wellness. Findings will provide important information to help in the development and/or optimization of early risk-mitigating intervention and prevention efforts to improve the quality of life for children.

Necrotizing enterocolitis (NEC) is the leading cause of death and disability in preterm infants. Despite advances in the care of neonates in general, the survival of infants with NEC remains low, in part due to our inability to predict which infants are at risk for the development of this disease.

The purpose of this focus group is to get feedback on an educational video about recovery from musculoskeletal pain. The information we learn may help us improve the video so that we can keep people from developing long-term opioid use.

The purpose of this research study is to test a set of interventions designed to improve HIV care and prevention among girls and young women in Zambia.

This study is looking to compare the outcomes and cost of treating infected joints with surgery or aspiration with a needle combined with injection of antibiotics. Many patients with infected joints are too sick to safely go to the operating room for surgery, thus we are investigating outcomes and cost of less invasive treatment options such as using a needle to aspirate the joint and inject antibiotics.

To assess the challenges and support needed to serve as a clinical champion for non-invasive ventilation in hospitals for patients with COPD

Purpose is to evaluate the ear tube simulator and compare to actual ear tube placement in patient.

The purpose of this study is to collect samples from patients with GI conditions that are coming to UNC for upper endoscopy as part of their clinical care. Samples will be stored and used for research to learn more about GI conditions.

To study the use of long-acting injectable antiretroviral therapy (LAI) among a racially, economically, and geographically diverse group of persons with HIV