The purpose of this study is to determine the efficacy of lactoferrin supplementation on iron regulation, gut health, immune function and physical activity performance.
My name is Halden Levin, and I am an undergraduate Linguistics major. For my honors thesis, I am investigating factors influencing speech production and perception in American English and Taiwanese Mandarin. Researching these factors will allow us to better understand speech production and perception.
The goal of this study is to understand how community and social connections may serve as protective factors for suicidal thoughts and behaviors in autistic and non-autistic individuals ages 55 and older. We aim to understand how both in-person and online social connections are associated with suicidal thoughts and behaviors. While a history of mental health concerns is required to participate in this study, a history of suicidal thoughts and behaviors is not required.
This study aims to understand how we can use fecal samples to measure cortisol levels in babies. Cortisol is used to measure stress biologically, and past research has used saliva or blood samples to do so. However, these measures can be hard to collect in infants, whereas diapers are relatively easy to obtain. We are aiming to determine whether cortisol in fecal samples changes throughout the day, like saliva or blood samples, or whether they are consistent like in urine. We will also use these data to investigate relationships between cortisol and composition of the gut microbiome, health, and infant distress. We are also measuring the composition of the skin microbiome to understand how the people a baby comes into contact with can affect their health.
We are studying an investigational drug, Efruxifermin, to see if it will help in the treatment of liver inflammation and scarring (fibrosis) in adults diagnosed with NASH (non-alcoholic steatohepatitis) and MASH (metabolic dysfunction-associated steatohepatitis).
We are studying an investigational drug, Efruxifermin, to see if it will help in the treatment of liver inflammation and scarring (fibrosis) in adults diagnosed with NASH (non-alcoholic steatohepatitis) and MASH (metabolic dysfunction-associated steatohepatitis).
Have you been diagnosed with Chronic Myeloid Leukemia, have a T315I mutation, and previously treated with at least two tyrosine kinase inhibitors (TKIs)? You might be able to participate in this study.
This research study is being done in participants with advanced B-cell malignancies such as some types of lymphomas or leukemias. B-cell malignancies express a protein called the Bruton's tyrosine kinase (BTK), which has been shown to help the tumor cells grow and survive. The investigational drug, AC676, has been designed to recognize the BTK protein, and marks it for destruction. By destroying the BTK protein, the malignancy may be stopped from growing. "Investigational" means the study drug being tested is not approved by the FDA. This is an open-label study, meaning all patients who are eligible to participate will receive study drug. The key purposes of this study are to: ● Test the study drug at different dose levels (dose-escalation) and to determine the highest dose that can be taken without side effects that can't be tolerated (referred to as maximum tolerated dose or MTD). ● Determine what dose of
The purpose of this research study is to compare the effectiveness of two combinations of anticancer study drugs in treating your Chronic Lymphocytic Leukemia (CLL). The first combination is sonrotoclax (also known as BGB-11417) and zanubrutinib, while the second combination is venetoclax and obinutuzumab. The aim is to determine which combination of study drugs is more effective in controlling your specific type of cancer,
Are you a male that has been diagnosed with hormone receptor positive and HER2 negative breast cancer? If so, you may be eligible to a clinical trial comparing different endocrine therapies to treat breast cancer prior to surgery.