You are being asked to take part in this study because you previously agreed to receive a U.S. Food and Drug Administration (FDA) approved drug, idecabtagene vicleucel (ide-cel), for the treatment of your disease as part of routine care and not a clinical research study. You had the blood collection (leukapheresis) (pronounced loo-ka-fer-ee-sis) procedure, your T cells (a subset of your white blood cells that are part of your immune system and attack things like infections and cancer cells) were collected and genetically modified in a laboratory in order to manufacture the ide-cel T cells for your disease treatment. The ide-cel T cells that were produced do not meet all of the prespecified release criteria to be used as a routine prescription drug as required by the governing health authority (such as the FDA) where you are being treated. For example, the modified T cells may have a lower cell

The purpose of this study is to determine the true prevalence of vision impairment (VI) and factors contributing to VI and blindness in North Carolina through screening and qualitative interviews.

The purpose of this research study is to assess the patient-level, healthcare provider/system-level, and community-level barriers to resolving abnormal mammograms and initiation of treatment of breast cancer in the 3 geographic regions of North Carolina: the greater Charlotte area, the Northwest, and the Northeast. These areas include the following counties: Anson, Cabarrus, Cleveland, Gaston, Lincoln, Mecklenburg, Stanly, Union, Edgecombe, Halifax, Nash, Northampton, Wilson , Ashe, Alleghany, Surry, Stokes, Watauga, Wilkes, Yadkin, Forsyth, Avery, Caldwell, Alexander, Iredell, Davie, Davidson, Burke, Catawba, and Rowan. These barriers can include obtainment of biopsies and other diagnostic procedures for resolving abnormal mammograms abnormalities or breast symptoms, access to care providers after breast cancer diagnosis, and initiation of appropriate surgical, chemotherapy, and radiation treatments after diagnosis.

The purpose of this study is to identify specific barriers to preventing a late stage cancer diagnosis within communities identified in North Carolina as having a higher rate of advanced cancer diagnoses.

The purpose of this study is to investigate the effectiveness of the use of case video review for post procedural feedback for training gynecology residents. The residents will also watch an expert narrated video of a hysterectomy.

To assess undergraduate and graduate student's attitudes regarding opioid overdose and harm reduction tools at a large, public university.

We are conducting interviews with residents and service providers across Edgecombe and Robeson Counties to support the development of the Whole Community Connection Program.

The primary endpoints are to determine the recommended phase 2 dose (RP2D) of SNDX-5613 administered in combination with chemotherapy in patients with relapsed or refractory KMT2A-rearranged (KMT2A-R) acute lymphoblastic leukemia (ALL), and to estimate the minimal residual disease (MRD) negative remission rate of patients with R/R infant KMT2A-R ALL treated with SNDX-5613 in combination with chemotherapy. Secondary endpoints include characterizing the pharmacokinetics (PK) of SNDX-5613 administered with chemotherapy in patients with R/R infant KMT2A-R ALL, estimating the 18-month event-free survival (EFS) of patients with R/R infant KMT2A-R ALL treated with SNDX5613 in combination with chemotherapy, estimating 18-month overall survival (OS) of patients with R/R infant KMT2A-R ALL treated with SNDX5613 in combination with hemotherapy, and characterizing the tolerability of SNDX-5613 given as monotherapy in patients with R/R infant KMT2A-R ALL. The exploratory endpoint is to assess the biologic activity of SNDX-5613 administered with chemotherapy in patients with R/RKMT2A-R ALL.

This study aims to understand how archaeologists keep records of their discoveries and artifacts. The goal is to discover the best ways to teach archaeologists about organizing and saving information relevant to their excavations. The study considers examples from the past and present and will rely on discussions with specialists and the analysis of the "Work Digital / Think Archive" guidebook made jointly by DigVentures and the Archaeological Archives Forum. The goal is to spread the word about the efforts happening now to set up the best frameworks and workflows for archaeologists to handle their digital data and create intentional standards for preserving their findings.

We are studying a patient's own opinion of their scar and the symptoms that their scar causes them alongside photographs of the scar to assess wound healing.