Do you have bladder cancer that has spread to nearby tissue or other parts of the body? You may be able to participate in a research study to find out if the investigational drug disitamab vedotin alone or with pembrolizumab works to treat bladder cancer.

The UNC MOTION Science Institute is seeking volunteers with a history of anterior cruciate ligament (ACL) reconstruction surgery and healthy controls for a research study on the effects of stroboscopic vision on walking gait biomechanics, and how the somatosensory function may influence these changes. Individuals who have injured their ACLs are at a high risk of developing post-traumatic osteoarthritis, in part due to altered gait biomechanics. Stroboscopic vision has been shown to alter biomechanics in other tasks and populations, but its effects on walking biomechanics following ACL reconstruction is unknown.

Have you been diagnosed with Multiple Myeloma? Have you received idecabtagene vicleucel (ide-cel (Abecma)) CAR-T treatment? If so, you may be able to take part in a research study looking at for how long a new drug called iberdomide will keep Multiple Myeloma under control (in remission).

This study aims to understand how a person's race and where they live affect the quality of breast cancer care they receive. We invite Black and/or African American breast cancer patients and survivors from specific areas of North Carolina to participate in a virtual focus group. The purpose of this focus group is to get your feedback about maps and other tools our team has created to show how breast cancer care quality varies around the state and by race. We also want to hear your experiences seeking care in your area, and your ideas about possible reasons behind the patterns in your area.

Have you been diagnosed with large B-cell lymphoma (LBCL) and have not yet received treament? If so, you may be able to take part in a research study looking at the efficacy of giving a drug called glofitamab in combination with other drugs. The drugs are: polatuzumab vedotin (Pola) (also known as Polivy→) and rituximab (R) (also known as Rituxan→ and MabThera→), as well as a group of chemotherapy drugs, cyclophosphamide (C), doxorubicin (H), and prednisone (P) (referred to as Pola-R-CHP).

What factors influence how the brain takes in sugar to use it as energy? If you are between the ages of 18-45 years old and are healthy and of normal weight, you might be eligible to participate in this study to help us understand how the way sugar enters the body affects how sugar enters the brain.

Focus groups for adolescents and caregivers who have had eating disorders or disordered eating to help us develop a new treatment that is appropriate for members of the Latinx community.

In this study, we will look at how clinics give care to patients of all body sizes. We will talk to doctors and clinic staff to find out their policies and how they provide care that includes everyone.

Collect Biospecimens from subjects who are newly diagnosed with Acute Myeloid Leukemia (AML)

This is a clinical research study to learn more about a drug being developed to treat Hidradenitis Suppurativa. We want to learn more about how this study drug affects those with Hidradenitis Suppurativa.