The purpose of this study is to find out if an investigational medication (NBTXR3) could help elderly patients with locally advanced head & neck squamous cell carcinoma who are otherwise ineligible to receive platinum-based chemotherapy. This study will help to determine the recommended dose/s of NBTXR3. The study medication is injected directly into the tumor and is activated by radiation therapy in combination with anti-PD1 therapy.

Do you have newly-diagnosed multiple myeloma? If so, you may be able to participate in a research study looking at the safety, efficacy, and tolerability of giving isatuximab in combination with lenalidomide and dexamethasone at lower doses.

Have you been diagnosed with multiple myeloma that has not responded to treatment or has come back after treatment? If so, you may be able to take part in a research study looking at the safety and efficacy of giving a new drug called ABBV-383 to patients with relapsed/refractory multiple myeloma.

The purpose of this observational study is to follow Endometrial Cancer patients through standard of care treatment of their Endometrial Cancer and collect biomedical and patient reported outcomes data.

The purpose of this study is to compare the effectiveness of the drug megestrol alone, or combined with metformin, on the growth of Endometrial Intraepithelial Neoplasia.

Have you been diagnosed with uterine cancer called endometrial serous carcinoma or carcinosarcoma? If so, you may be able to take part in a research study to test if adding a drug or drugs that target HER2 proteins in addition to the usual combination of chemotherapy drugs could prevent your cancer from returning or shrink your cancer.

Have you been diagnosed with Metastatic Castration-Resistant Prostate Cancer. If so, you may be able to take part in a research study looking at the safety of giving Docetaxel vs Docetaxel and Radium-223 to patients.

Are you receiving initial treatment for non-small cell lung cancer or invasive squamous cell carcinoma of the head and neck and want to participate in research that aims to improve treatment and care of future patients with the same diagnosis? If so, you may be able to participate in a study for an investigational blood test to predict whether your cancer will come back.

Do you have known or suspected lung and/or head and neck cancer? Are you scheduled for a tumor biopsy? If so, you may be able to participate in a research registry aimed at learning more about lung and head/neck cancer.

In this study, we want to learn more about the safety and effectiveness of using a personalized vaccine with a drug called pembrolizumab for the treatment of non‐small cell lung cancer (NSCLC) and squamous cell cancer of the head and neck (SCCHN).