The purpose of the PREPARE Project is to advance the health interests of pregnant adolescents living with or at risk of HIV through building on the work of PHASES to develop an empirically informed Ethics Guidance to facilitate timely, responsible research with pregnant adolescents.

Community health assessments (CHA) are used to identify key health needs and issues through systematic, comprehensive data collection, and analysis. Commonly these assessments focus on disease and injuries causes the most health risk in the community of focus. Determinants of health are also included in a CHA. These determinants may include environmental factors. However the inclusion of a full environmental assessment in a CHA is very uncommon. Despite the potential of CHAs to assess cumulative impacts, limited environmental data weakens their effectiveness. The Lumbee Tribe recently conducted a Tribal Health Assessment and it included only one question about environmental quality. This research aims to identify what should be included in a future Tribal Environmental Health Assessment.

Is polycystic ovary syndrome (PCOS) making it difficult for you to get pregnant? Are you trying to get pregnant as soon as possible? You may be able to participate in a research study to find out if a new device can help restore fertility in women with PCOS. Compensation provided.

Do you ever feel discomfort during your pessary check-ups? Are you looking for ways to make them more comfortable? If you are a woman experiencing discomfort during pessary exams, you may be able to take part in our research study. We are seeing if massaging the area around the opening of the vagina (perineal massage) could help lessen pain during pessary exams. Compensation provided.

You are being asked to participate in this research study because you have been diagnosed with breast cancer and considered for immunotherapy. This study will investigate your response to immunotherapy.

If you are being considered for an EXIT procedure, you may be eligible to participate in our research study.

Do you have triple-negative breast cancer that either came back or did not improve after initial cancer treatment? If so, you may be able to take part in this gene therapy research study to learn more about using your own modified immune cells as a possible treatment.

Have you recently had an anterior cruciate ligament injury and will be undergoing anterior cruciate ligament reconstruction surgery? If so, you may be able to participate in a study comparing the effects on pain relief and arthritis prevention of metformin or placebo. Compensation provided.

The purpose of this study is to see if batoclimab is safe and helps people with chronic inflammatory demyelinating polyneuropathy (CIDP), an autoimmune disorder. Batoclimab is also known as IMVT-1401. Batoclimab is injected under the skin (subcutaneously) and targets the immune system.

Are you interested in improving your physical health and wellbeing during or after cancer treatment? If so, our free 12- week exercise program might be a good fit for you! We are creating a registry of adults with a cancer diagnosis who have gone through our program.