In this study, we want to find a better treatment for advanced melanoma. We want to see how well two different drugs work compared to the regular treatment.

The purpose of this research study is to improve cancer care for patients whose treatment outcomes have led to challenges in their quality of life. The study is randomized into 2 groups. Group 1 will receive a pre-rehabilitation referral in addition to their standard of care cancer treatment and Group 2 will resume their standard of care cancer treatment. Regardless of the group you are assigned to, all participants will answer questionnaires at baseline and at their 3-month follow-up.

Does hypertonic saline improve mucus clearance in bronchiectasis? The purpose of this research study is to evaluate the effects of 7% hypertonic saline (HS) delivered by nebulizer on clearance of mucus from the lungs in people with bronchiectasis. We will compare mucociliary clearance (MCC: a measurement of the rate at which a person's lungs can clear inhaled particles) at baseline, after a single dose of HS, and after two weeks of treatment with HS twice a day. We will also assess response to HS with other outcomes (spirometry, multiple breath washout [MBW], changes in sputum [coughed up mucus or phlegm], and survey responses). Compensation provided. No blood draws required.

Feeling depressed? Join our clinical research study today to help assess the feasibility and performance of a novel noninvasive brain stimulation device in individuals experiencing depressive symptoms. Compensation provided.

Have you given birth before? Are you an adult? If so, you may be able to participate in a study to see if postpartum depression and/or postpartum psychosis have a genetic cause. We want to ultimately find a cure. Help us stop postpartum depression. Compensation provided.

The purpose of this research study is to gain insight into how people interact with some of Spotify's features including Discover Weeklyl, DJ, and Daylist. We want to learn more about the factors that influence how users discover new music when using these features.

The purpose of this research study is to investigate how human interpret some predictive learned by AI systems when detecting deceptive hotel reviews and how AI explanations can shape human understanding. For instance, the AI system learns that words like "floor" and "bathroom" are highly predictive of genuine reviews and words like "husband" and "luxury" are highly predictive of deceptive reviews. While the AI system highlights these words by learning from the data, the association between these words and the outcome are not easy to comprehend for humans. Thus, our goal of this research is to investigate how participants interact with machine-generated explanations that are unintuitive, and how participants make use of our developed visualizations and tools to make sense of these unintuitive features.

The purpose of this study is to test the safety and effectiveness of the test drug IMGN151-1001 on your cancer.

Do you drink alcohol regularly? Do you own an iPhone with Apple iOS 6 or higher? If so, you may be able to take part in a study looking at responses to alcohol and drinking behavior in people who drink alcohol regularly. We want to see how people's bodies react to alcohol in the lab and outside of it. Compensation provided.

In this study, we want to see how giving birth affects stress chemicals in the body. We will focus on a stress hormone called cortisol and check its levels in people who gave birth, from 3 to 12 months after giving birth.