Cyclophosphamide is a chemotherapy (chemo) drug often given after a transplant to prevent GvHD. We are doing this study to see if a lower dose of cyclophosphamide after transplant is safer, but just as effective. Cyclophosphamide can prevent GvHD, but it can also make you sick and more likely to get an infection. This study will look at how well a lower dose of cyclophosphamide works to reduce these side effects, while also preventing GvHD. This study does not include any new or untested drugs. The drugs and procedures in this study are standard for transplant.
The study treatment, finerenone, is being developed to help people who have long lasting kidney disease, also known as chronic kidney disease (CKD). It works by blocking a certain hormone called aldosterone that causes injury and inflammation in the heart and kidney which is known to play a role in CKD. In this study, the researchers want to learn if finerenone works the same way in kidney transplant recipients. Some subjects will receive the study drug and some will receive a placebo.
Do you have pancreatic ductal adenocarcinoma that has come back after receiving standard therapy? If so, you may be able to participate in this gene therapy research study to learn more about using you own modified immune cells as possible treatment.
This study will evaluate the feasibility of using capillary blood samples collected with the Tasso device for analysis of CBC in diseased patients with leukemia, lymphoma, and/or other blood cell disorders.
Through in-person and remote, hour-long interviews, this research study aims to understand how the how young people in the United States experience social media.
Have you been diagnosed with a B cell disease that has returned after your previous treatment or is not responding to your current treatment? If so, you might be able to take part in a study to see if a new treatment is safe and can help treat people with B-cell diseases.
You will be informed of the purpose of this study at the end of the survey.
The purpose of this study is to identify why households waste food. Using these causes of household food waste, we will work with participants to develop a comprehensive packet of tools that can be implemented in their daily lives to prevent food waste.
Do you have cervical cancer and are confused about health insurance or paying for your healthcare? We want to hear your thoughts on what might make it easier to navigate the financial side of cancer treatment. Your participation will help us to build a program to help cervical cancer patients like you. Compensation provided.
This research study aims to use electroencephalography (EEG) to refine our understanding of the neural mechanisms involved in suppressing distracting information.