The purpose of this study is to test good and bad effects of different drugs against metastatic brain tumors with altered genes. This trial is trying to see if tumor genetic testing would be helpful at guiding treatment in patients such as you. Researchers have looked at the DNA material (genes) that can be affected in brain metastases and have found several genes that are altered, or mutated. There are medications that target these genes. We are doing this study because we want to find out if this approach is better or worse than the usual approach for your metastatic cancer. The usual approach is defined as care most people get for your metastatic cancer.

Have you been diagnosed with extremity soft tissue sarcoma and are scheduled to have standard of care radiotherapy (XRT) followed by surgery to treat your cancer? XRT is effective in managing extremity soft tissue sarcoma, however, it is associated with risks, such as damage to healthy tissue, and complications in post-surgery wound healing.

We are trying to understand responses to food labels among adults who identify as Hispanic/Latino.

Did you have head or neck cancer? Have you completed radiation in the past 3 years or more and now have dry mouth? You may be able to take part in a research study to help us learn if a gene therapy can help people with dry mouth due to radiation therapy.

Have you been diagnosed with high-risk early triple-negative breast cancer (TNBC) without mutations in the BRCA1 or BRCA2 gene? If you still have evidence of TNBC in your breast or lymph node tissue after receiving treatment and surgery, you may qualify for this clinical research study. This study will test an experimental drug combination to find out which treatment is better at delaying the return of cancer.

If you are healthy and between the ages of 18-55 years, you may be eligible to participate in a research study to find out how sugar affects the brain of individuals who carry certain genetic variants.

Are you scheduled for weight loss surgery within the next 12 months? You may be able to take part in a research study to help us learn more about your metabolic hormones, eating behaviors, stress, and weight loss before and after your surgery.

The goal of this study is to create a support group and resources for adolescents who identify as both autistic and gender diverse using input from adolescents, parents, and professionals.

Do you have Cutaneous Lupus Erythematosus (CLE)? If you have tried antimalarials but they haven't helped your skin get better, you may be able to take part in a research study. In this study, we want to find out if a new drug improves the skin of patients with CLE. Compensation provided.

Nutrition is not one-size-fits-all. Nutrition, or the foods we eat, can help prevent and fight conditions such as high blood pressure, diabetes, stroke, and more. However, we all live in different environments, we come from different cultures, and each of us is starting from a different place with our health. Additionally, everyone breaks down food differently. Join the Nutrition for Precision Health research study to help researchers learn how our genes, cultural backgrounds, and environments affect our bodies' responses to food. Compensation provided.