Have you had depression for at least 3 months? If your depression has not improved with two antidepressants, you may be able to take part in a research study to learn more about psilocybin-assisted therapy.

This study will try to see what the association is between older adults using a GLP-1 agonist medication and their physical function.

Do you have glioblastoma? Has your cancer either come back or did not improve after the treatments you received? If so, you may be eligible to participate in this gene therapy research study that wants to learn if a new way to modify your immune cells for use as possible treatment is safe and at what dose.

We want to know what people think about gender and how pronouns are used in American English.

The proposed study seeks to understand how Black transgender and/or nonbinary students attending a PWI view the concept of coming out, and how that relates to their identity as a Black transgender individual.

The purpose of this research study is to explore key periods of family life over time among adults who have experience parenting at least one child from birth to young adulthood. Study findings could help inform the development of programs and services that are intended to benefit children and families.

The purpose of this project is to adapt and confirm a tool is effective for measuring change in communication for young children on the autism spectrum.

Are you interested in how changes in shoes and footwear can be used to make improvements to day-to-day life? You may be able to participate in a research study to quantify the biomechanical effects of different footwear on walking. Compensation provided.

In this study, we want to use an online survey for people newly diagnosed with metastatic breast cancer to ask questions about physical and emotional health. We hope to use the results of this survey to design a program to help future patients tolerate treatment better.

We have study goals: (1) To conduct phone interviews to ask about symptoms and life impact from adult patients living with PSC; (2) To lead community advisory board discussions to decide on using existing symptom measures 'as is', modify existing measures or develop new measures to evaluate PSC symptoms; and (3) To conduct interviews with adult patients with PSC to assess their understanding and comprehension of selected symptom measures. We plan to consent and enroll up to 75 patients into a Screening database. From the database, we will select up to 24 patients to interview for Aim 1 and up to 16 patients to interview for Aim 3. Interviews will be conducted over the phone by staff at Duke University. At the end of the study, we will have 3 PSC symptom measures for use in future PSC studies.